Yazar "Uzun, Meltem" için listeleme
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Comparative evaluation of the microplate nitrate reductase assay and the rezasurin microtitre assay for the rapid detection of multidrug resistant Mycobacterium tuberculosis clinical isolates
Coban, Ahmet Yilmaz; Uzun, Meltem; Akgunes, Alper; Durupinar, Belma (Fundaco Oswaldo Cruz, 2012)The microplate nitrate reductase assay (MNRA) and the rezasurin microtitre assay (REMA) were used for the susceptibility testing of 73 clinical isolates and the results were compared with those that were obtained using the ... -
Comparative Study for Determination of Mycobacterium tuberculosis Susceptibility to First- and Second-Line Antituberculosis Drugs by the Etest Using 7H11, Blood, and Chocolate Agar
Coban, Ahmet Yilmaz; Bilgin, Kemal; Uzun, Meltem; Akgunes, Alper; Yusof, Anne; Durupinar, Belma (Amer Soc Microbiology, 2008)We investigated the performance of blood and chocolate agar as alternatives to Middlebrook 7H11 agar for testing the susceptibility of Mycobacterium tuberculosis to first-and second-line drugs by the Etest method. A total ... -
Effect of Linezolid in Combination With Isoniazid and Rifampicin Against Multidrug Resistant Mycobacterium Tuberculosis Clinical Isolates
Coban, Ahmet Yilmaz; Bilgin, Kemal; Uzun, Meltem; Durupinar, Belma (Ankara Microbiology Soc, 2009)Tuberculosis continues to be a serious public health problem worldwide. Since multi-drug resistant strains of Mycobacterium tuberculosis constitutes a serious problem in tuberculosis control, new and more effective ... -
Evaluation of Agar-Based Medium with Sheep Sera for Testing of Drug Susceptibility of Mycobacterium tuberculosis to Isoniazid, Rifampin, Ethambutol, and Streptomycin
Coban, Ahmet Yilmaz; Uzun, Meltem; Bozdogan, Bulent (Amer Soc Microbiology, 2013)The performance of sheep sera instead of sheep blood in agar-based media was investigated for susceptibility testing of Mycobacterium tuberculosis against primary drugs. The levels of agreement between agar-based medium ... -
Evaluation of crystal violet decolorization assay for minimal inhibitory concentration detection of primary antituberculosis drugs against Mycobacterium tuberculosis isolates
Coban, Ahmet Yilmaz; Akbal, Ahmet Ugur; Uzun, Meltem; Cayci, Yeliz Tanriverdi; Birinci, Asuman; Durupinar, Belma (Fundaco Oswaldo Cruz, 2016)In this study we evaluated the crystal violet decolorization assay (CVDA) for detection of minimum inhibitory concentration (MIC) of antituberculosis drugs. 53 isolates were tested in this study and 13 of them were multidrug ... -
Evaluation of four colourimetric susceptibility tests for the rapid detection of multidrug-resistant Mycobacterium tuberculosis isolates
Coban, Ahmet Yilmaz; Akbal, Ahmet Ugur; Uzun, Meltem; Durupinar, Belma (Fundaco Oswaldo Cruz, 2015)The purpose of this study is to evaluate four rapid colourimetric methods, including the resazurin microtitre assay (REMA), malachite green decolourisation assay (MGDA), microplate nitrate reductase assay (MNRA) and crystal ... -
In vitro effect of tigecycline against Mycobacterium tuberculosis and a review of the available drugs for tuberculosis
Coban, Ahmet Yilmaz; Deveci, Aydin; Cayci, Yeliz Tanriverdi; Uzun, Meltem; Akgunes, Alper; Durupinar, Belma (Academic Journals, 2011)The study aimed to investigate the effectiveness of a novel antibiotic drug tigecycline on clinical isolates of Mycobacterium tuberculosis and, reviewing defined anti-tuberculosis effects of available agents. Minimal ... -
Multicenter evaluation of crystal violet decolorization assay (CVDA) for rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis
Coban, Ahmet Yilmaz; Akbal, Ahmet Ugur; Bicmen, Can; Albay, Ali; Sig, Ali Korhan; Uzun, Meltem; Alp, Alpaslan (Nature Publishing Group, 2016)The aim of this multicenter study was to evaluate the performance of the crystal violet decolorization assay (CVDA) for detection of multidrug resistant tuberculosis (MDR-TB). This study was performed in 11 centers in two ... -
Multicenter Evaluation of the Indirect Nitrate Reductase Assay for the Rapid Detection of Multidrug-Resistant Tuberculosis
Coban, Ahmet Yilmaz; Tastekin, Berika; Uzun, Meltem; Kalayci, Fatma; Ceyhan, Ismail; Bicmen, Can; Alp, Alparslan (Ankara Microbiology Soc, 2016)Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to at least isoniazid (INH) and rifampicin (RIF), and it complicates the implementation of tuberculosis control programmes. The rapid detection of MDR-TB ... -
A new colorimetric method for rapid detection of ethambutol and streptomycin resistance in Mycobacterium tuberculosis: crystal violet decolorization assay (CVDA)
Coban, Ahmet Yilmaz; Akbal, Ahmet Ugur; Ceyhan, Ismail; Uzun, Meltem; Selale, Deniz Sertel; Aslan, Gonul; Surucuoglu, Suheyla (Springer, 2019)Streptomycin (STR) and ethambutol (EMB) are important drugs used for the treatment of tuberculosis. There is a need for fast, reliable and inexpensive methods for detecting resistance to these drugs. The aim of this study ... -
A rapid detection of multidrug-resistant Mycobacterium tuberculosis by a nitrate reductase assay on blood agar
Coban, Ahmet Yilmaz; Cayci, Yeliz Tanriverdi; Deveci, Aydin; Akgunes, Alper; Uzun, Meltem; Durupinar, Belma (Fundaco Oswaldo Cruz, 2011)The susceptibility of 49 Mycobacterium tuberculosis clinical isolates to isoniazid (INH) and rifampisin (RIF) (28 multi-drug resistant-tuberculosis samples) was determined by a nitrate reductase assay (NRA) on blood agar. ... -
Rapid detection of multidrug-resistant Mycobacterium tuberculosis using the malachite green decolourisation assay
Coban, Ahmet Yilmaz; Uzun, Meltem (Fundaco Oswaldo Cruz, 2013)Early detection of drug resistance in Mycobacterium tuberculosis isolates allows for earlier and more effective treatment of patients. The aim of this study was to investigate the performance of the malachite green ... -
Testing Susceptibility of Multidrug-Resistant Mycobacterium tuberculosis to Second-Line Drugs by Use of Blood Agar
Satana, Dilek; Coban, Ahmet Yilmaz; Uzun, Meltem (Amer Soc Microbiology, 2010)In this study, the susceptibilities of 35 multidrug-resistant (MDR) Mycobacterium tuberculosis clinical isolates to second-line drugs, including kanamycin (KM), rifabutin (RBU), ofloxacin (OFX), p-aminosalicylic acid (PAS), ...
