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Functionalized imidazolium and benzimidazolium salts as paraoxonase 1 inhibitors: Synthesis, characterization and molecular docking studies

Karatas, Mert Olgun; Uslu, Harun; Alici, Bulent; Gokce, Basak; Gencer, Nahit; Arslan, Oktay; Özdemir, Namık (Pergamon-Elsevier Science Ltd, 2016)

Paraoxonase (PON) is a key enzyme in metabolism of living organisms and decreased activity of PON1 was acknowledged as a risk for atherosclerosis and organophosphate toxicity. The present study describes the synthesis, ...