Yazar "Talaz, Oktay" için listeleme
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alpha-Carbonic anhydrases are sulfatases with cyclic diol monosulfate esters
Cavdar, Huseyin; Ekinci, Deniz; Talaz, Oktay; Saracoglu, Nurullah; Senturk, Murat; Supuran, Claudiu T. (Taylor & Francis Ltd, 2012)Carbonic anhydrases (CA) catalyze activated ester hydrolysis in addition to the hydration of CO 2 to bicarbonate. They also show phosphatase activity with 4-nitrophenyl phosphate as substrate but not sulfatase with the ... -
Determination of the inhibitory effects of N-methylpyrrole derivatives on glutathione reductase enzyme
Kocaoglu, Esma; Talaz, Oktay; Cavdar, Huseyin; Senturk, Murat; Supuran, Claudiu T.; Ekinci, Deniz (Taylor & Francis Ltd, 2019)Glutathione reductase (GR) is a crucial antioxidant enzyme which is responsible for the maintenance of antioxidant GSH molecule. Antimalarial effects of some chemical molecules are attributed to their inhibition of GR, ... -
Structure-activity relationships for the interaction of 5,10-dihydroindeno[1,2-b] indole derivatives with human and bovine carbonic anhydrase isoforms I, II, III, IV and VI
Ekinci, Deniz; Cavdar, Huseyin; Durdagi, Serdar; Talaz, Oktay; Senturk, Murat; Supuran, Claudiu T. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2012)Several 5,10-dihydroindeno[1,2-b]indole derivatives incorporating methoxy, hydroxyl, and halogen (F, Cl, and Br) moieties on the indene fragment of the molecule were prepared and tested against five carbonic anhydrase (CA, ... -
Synthesis of 1,4-bis(indolin-1-ylmethyl)benzene derivatives and their structure-activity relationships for the interaction of human carbonic anhydrase isoforms I and II
Talaz, Oktay; Cavdar, Huseyin; Durdagi, Serdar; Azak, Hacer; Ekinci, Deniz (Pergamon-Elsevier Science Ltd, 2013)Several 1,4-bis(indolin-1-ylmethyl)benzene-based compounds containing substituents such as five, six and seven cyclic derivatives on indeno part (9a-c) were prepared and tested against two members of the pH regulatory ... -
Synthesis of 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives and evaluation of the carbonic anhydrase I and II inhibition
Arslan, Mehmet; Senturk, Murat; Fidan, Ismail; Talaz, Oktay; Ekinci, Deniz; Cosgun, Sedat; Supuran, Claudiu T. (Taylor & Francis Ltd, 2015)The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I and II, with some 3,4-dihydroxypyrrolidine-2,5-dione and 3,5-dihydroxybenzoic acid derivatives, were investigated by using the esterase ... -
Synthesis of novel mono and bis-indole conduritol derivatives and their alpha/beta-glycosidase inhibitory effects
Cavdar, Huseyin; Talaz, Oktay; Ekinci, Deniz (Pergamon-Elsevier Science Ltd, 2012)Here we synthesized four novel indole conduritol derivatives 1-4 for the first time in the literature and probed their biological activities with the alpha and beta-glucosidases. The compounds showed quite effective ...
