Yazar "Sozmen, Mahmut" için listeleme
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Alpha basic crystallin expression in canine mammary tumors
Guvenc, To Iga; Gulbahar, Mustafa Yavuz; Yarim, Murat; Kabak, Yonca Betil; Karayigit, Onder; Sozmen, Mahmut (Korean Soc Veterinary Science, 2012)The aim of this study was to evaluate prognostic and/or diagnostic factors of canine mammary tumors by immunohistochemically analyzing the expression of alpha basic crystallin (alpha B-c). For this, formalin-fixed, ... -
The effects of dexmedetomidine on mesenteric arterial occlusion-associated gut ischemia and reperfusion-induced gut and kidney injury in rabbits
Kilic, Kemal; Hanci, Volkan; Selek, Sahbettin; Sozmen, Mahmut; Kilic, Nergiz; Citil, Mehmet; Yurtlu, B. Serhan (Academic Press Inc Elsevier Science, 2012)Objective: We assessed the antioxidant activity of dexmedetomidine (Dex) administered during the ischemic period in a rabbit model of mesenteric ischemia/reperfusion (I/R) injury using biochemical and histopathological ... -
The Effects of Gemfibrozil and Ovariectomy on the Peroxisome Proliferator Activated Receptors (PPARs) in Mice with Experimentally Induced Obesity
Tunca, Recai; Devrim, Alparslan Kadir; Sozmen, Mahmut; Dag, Serpil; Gungor, Orsan; Ipek, Emrah (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)Effects of gemfibrozil and ovariectomy on Peroxisome Proliferator Activated Receptors (PPARs) activity were studied in obese mice. Ovariectomised and sham operated mice were fed with high fat diet and low fat diet for 15 ... -
Effects of Insulin and Embryonic Stem Cells Loaded Plga Nanoparticles on Pancreatic Beta Tc Cells
Yucel, Cigdem; Aktas, Yesim; Degim, Zelihagul; Yilmaz, Sukran; Arsoy, Taibe; Altintas, Levent; Sozmen, Mahmut (Polskie Towarzystwo Farmaceutyczne, 2018)The present study, aims to investigate and compare the effect of insulin and embryonic stem cells (ESC) loaded nanoparticle formulations (NPs) on pancreatic-beta-TC-cell regeneration. Characterization studies of NPs were ... -
The Effects of Periostin in a Rat Model of Isoproterenol: Mediated Cardiotoxicity
Sozmen, Mahmut; Devrim, Alparslan K.; Kabak, Yonca B.; Devrim, Tuba; Sudagidan, Mert (Humana Press Inc, 2018)Periostin is an extracellular matrix protein from fasciclin family, and it plays an important role in the cell adhesion, migration, and growth of the organism. Periostin prevents apoptosis while stimulating cardiomyocytes. ... -
Efficacy of targeted liposomes and nanocochleates containing imatinib plus dexketoprofen against fibrosarcoma
Coban, Ozlenn; Degim, Zelihagul; Yilmaz, Sukran; Altintas, Levent; Arsoy, Taibe; Sozmen, Mahmut (Wiley, 2019)The main challenges in treating cancer using chemotherapeutics are insufficient dose at the target site and the development of drug resistance, while higher doses can induce side effects by damaging nontarget tissues. ... -
Evaluation of Clinical, Radiological and Pathological Findings in the Identification of a Spinal Cord Lesion in a Paraplegic Dog
Kilic, Engin; Yayla, Sadik; Ermutlu, Celal Sahin; Kaya, Miktat; Aygun, Hayati; Sozmen, Mahmut (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)The aim of this report describes the identification of an interesting spinal cord lesion developing in a 2 years old, male, hybrid dog due to being injured by gunshot. In the direct radiography of the patient diagnosed ... -
Gastric Helicobacter-like Organisms in Stray Cats: Identification, Prevalence, and Pathologic Association
Dag, Serpil; Sozmen, Mahmut; Cihan, Mete; Tunca, Recai; Kurt, Basak; Devrim, Alparslan Kadir; Ozen, Hasan (Univ Agriculture, Fac Veterinary Science, 2016)Total of 30 domestic stray cats (Felis cattus) were investigated for the presence of different species of gastric Helicobacter-like organisms (GHLO) by immunohistochemistry and polymerase chain reaction (PCR) analysis. The ... -
Heterotopic Allogenic and Autogenic Ovarian Transplantation in Rabbits: Assessment and Comparison of the Morphological and Endocrine Characteristics
Temur, Ismail; Ulker, Kahraman; Ermutlu, C. Sahin; Gul, Abdulaziz; Huseyinoglu, Urfettin; Cihan, Mete; Sozmen, Mahmut (Kafkas Univ, Veteriner Fakultesi Dergisi, 2013)The aim of this study was to evaluate and compare the endocrine function and morphological characteristics of subcutaneous heterotopic allogenic and autogenic ovarian transplantation in immune-suppressed rabbits. Each group ... -
A Histopathological, Immunohistochemical and Molecular Study of Cutaneous Bovine Papillomatosis
Tan, Mehmet Tolga; Yildirim, Yakup; Sozmen, Mahmut; Bilge Dagalp, Seval; Yilmaz, Volkan; Kirmizigul, Ali Haydar; Gokce, Erhan (Kafkas Univ, Veteriner Fakultesi Dergisi, 2012)In animals and man, some forms of cutaneous papillomas are caused by papillomaviruses. Twelve different genotypes of bovine papillomavirus (BPV) have been identified. BPV-1 through BPV-12 are all strictly species-specific. ... -
Hyaluronic acid and synovial fluid in preventing adhesion formation after tenorrhaphy: An in vivo study on rabbit Achilles tendon
Kurt, Basak; Ozaydin, Isa; Sozmen, Mahmut; Bilge, Ali; Cihan, Mete; Hamamci, Emre; Aydin, Ugur (Univ Federal Santa Maria, 2018)Peritendinous adhesions are a significant problem in tendon surgery. One of the most preferred methods for preventing adhesion formation is anti-adhesive applications. This study aimed to investigate the efficacy of natural ... -
Immunohistochemical distribution of COX-1 and COX-2 in the liver to during the puberty period of rats applied with capsaicin
Nur, Gokhan; Yildiz, Sevda Elis; Nazli, Mumtaz; Sozmen, Mahmut (Ankara Univ Press, 2015)In this study, the effect of capsaicin on the immunohistochemical distribution of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) were examined in liver of the rat at the pubertal age. Thirty rats (Sprague-Dawley) ... -
Immunohistochemical examination on the effects of malathion and Onosma nigricaule (Boraginaceae) on the catalase (CAT) and superoxide dismutase-2 (Mn-SOD) in renal tissues of mice
Bakir, Buket; Erdag, Dincer; Elis Yildiz, Sevda; Karadag Sari, Ebru; Asker, Hasan; Sozmen, Mahmut (Ankara Univ Press, 2017)The purpose of this study was to determine the effects of the plant extract, which is obtained from Onosma nigricaule due to the oxidation parameters caused in mice by malathion that is used as an insecticide in agriculture, ... -
Inducible nitric oxide synthase expression in cerebellum of dogs naturally infected with canine distemper virus
Yarim, Murat; Karayigit, M. Onder; Gacar, Ayhan; Kabak, Yonca B.; Gulbahar, M. Yavuz; Guvenc, Tolga; Sozmen, Mahmut (Ankara Univ Press, 2015)The aim of this study is to investigate of inducible nitric oxide synthase (iNOS) and nitrotyrosine (NT) expression in the cerebellum of dogs naturally infected with canine distemper virus (CDV), a disease characterized ... -
Investigation of Protective Effect of L-Carnitine on L-Asparaginase-Induced Acute Pancreatic Injury in Male Balb/c Mice
Kaya, Inan; Citil, Mehmet; Sozmen, Mahmut; Karapehlivan, Mahmut; Cigsar, Gulsen (Springer, 2015)Introduction The present analysis deals with the biochemical and histopathological effects of L-carnitine in mice with L-asparaginase (ASNase)-induced experimental acute pancreatic injury (API). Methods A total of 32 male ... -
Investigation of the effect of cornelian cherry (Cornus mas L.) fruit extract against cisplatin-induced renal cell injury in vitro
Yarim, Gul Fatma; Kazak, Filiz; Sozmen, Mahmut; Koca, Ilkay; Albayrak, Harun; Yarim, Murat; Ozan, Emre (Walter De Gruyter Gmbh, 2017)Objective: The aim of this study was to evaluate the protective effects of cornelian cherry fruit extract against cisplatin- induced nephrotoxicity in vitro. Materials and methods: African green monkey kidney epithelial ... -
Novel Approach to the Treatment of Diabetes: Embryonic Stem Cell and Insulin-Loaded Liposomes and Nanocochleates
Yucel, Cigdem; Aktas, Yesim; Degim, Zelihagul; Yilmaz, Sukran; Arsoy, Taibe; Altintas, Levent; Sozmen, Mahmut (Amer Scientific Publishers, 2019)This study aims to investigate and compare the effects of insulin and embryonic stem-cell (ESC) loaded liposomes (LPs) and nanocochleate formulations and their PEGylated forms on the glucose levels. All formulations were ... -
Pre-pubertal treatment with a GnRH agonist in bitches-Effect on the uterus and hormone receptor expression
Schafer-Somi, Sabine; Kaya, Duygu; Sozmen, Mahmut; Kaya, Semra; Aslan, Selim (Wiley, 2018)Contents Aim of the study was to examine the effect of deslorelin on uterine tissues of eleven pre-pubertal bitches aged 4.2 +/- 0.6 m. Implants containing placebo (sodium chloride 0.9%; n = 4, G I), 4.7 mg (n = 3, GII) ... -
Protective effects of silymarin on fumonisin B-1-induced hepatotoxicity in mice
Sozmen, Mahmut; Devrim, Alparslan Kadir; Tunca, Recai; Bayezit, Murat; Dag, Serpil; Essiz, Dinc (Korean Soc Veterinary Science, 2014)The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B-1 (FB1) in BALB/c mice. The mice were divided into six groups (n = 15). Group 1 served as the ... -
Seroprevalance of Chlamydophila abortus in aborting ewes and dairy cattle in the north-east part of Turkey
Gokce, Halil Ibrahim; Kacar, Cihan; Genc, Oktay; Sozmen, Mahmut (Natl Veterinary Research Inst, 2007)The aim of the study was to determine the seroprevalance of Chlamydophila abortus in aborting ewes and cattle in the Kars province in the north-eastern part of Turkey. Thirty sheep flocks and 26 herds of dairy cattle out ...
