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Synthesis and Characterization of Some New Heteroaromatic Compounds Having Chirality Adjacent to a 1,3,4-Thiadiazole Moiety and Their Antimicrobial Activities

Gur, Mahmut; Sener, Nesrin; Kastas, Cigdem A.; Ozkan, Osman Emre; Muglu, Halit; Elmaswari, Magboule A. M. (Wiley, 2017)

Through a cyclization reaction of 2-phenylbutyric acid with N-phenylthiosemicarbazide and POCl3, novel 1,3,4-thiadiazole derivatives were synthesized. Their structures were confirmed using IR, H-1 NMR, and C-13 NMR ...