Yazar "Sefil, Fatih" için listeleme
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Anticonvulsant effect of carnosine on penicillin-induced epileptiform activity in rats
Kozan, Ramazan; Sefil, Fatih; Bagirici, Faruk (Elsevier Science Bv, 2008)Carnosine is a compound of naturally-occurring dipeptide that synthesized by the carnosine synthetase from beta-alanine and L-histidine. Recent reports claim that carnosine plays an important role in the control of epilepsy ... -
Demirin neden olduğu purkinje hücre kaybı üzerine nitrik oksit sentaz inhibisyonunun koruyucu etkisi
Amaç: Demir, nöronal hiperaktivite ve oksidatif stresi indüklemek için sıklıkla kullanılan bir metaldir. Nitrik oksit sentaz (NOS) tarafından sentezlenen nitrik oksit ile hücre ölümü arasındaki ilişkiyi ortaya koyan bulgular ... -
Effect of levetiracetam on penicillin induced epileptic activity in rats
Arik, Aliye Erguvan; Bagirici, Faruk; Sefil, Fatih; Marangoz, Cafer (Nencki Inst Experimental Biology, 2014)The aim of this study was to investigate the effects of levetiracetam (LEV) on penicillin- induced epileptiform activity in rats. Penicillin was applied intracerebroventricularly (icy) at a dose of 500 IU to induce ... -
Influence of carbenoxolone on the anticonvulsant efficacy of phenytoin in pentylenetetrazole kindled rats
Sefil, Fatih; Bagirici, Faruk; Acar, M. Dilek; Marangoz, Cafer (Nencki Inst Experimental Biology, 2012)Abnormal synchronized neuronal discharges mediated by gap junctions have an important role in epileptic seizures. The analysis of anticonvulsant drugs acting on gap junctions is still a priority in epilepsy research. ... -
Inhibition of neuronal nitric oxide synthase prevents iron-induced cerebellar Purkinje cell loss in the rat
Gulturk, Sefa; Kozan, Ramazan; Bostanci, M. Omer; Sefil, Fatih; Bagirici, Faruk (Nencki Inst Experimental Biology, 2008)Iron plays an important role in maintaining normal. brain function. However, in many neurodegenerative diseases abnormal iron accumulation in specific brain regions has been consistently reported. In this study, we ... -
Interaction between carbenoxolone and valproic acid on pentylenetetrazole kindling model of epilepsy
Sefil, Fatih; Arik, Aliye E.; Acar, Meryem D.; Bostanci, Mehmet O.; Bagirici, Faruk; Kozan, Ramazan (E-Century Publishing Corp, 2015)Gap junctions play an important role in the synchronized neuronal discharges. The main reason of the epileptic seizures is disruption of this synchronization. Therefore, the aim of the present study is to explore the ... -
Seizures with Pentylenetetrazoll indling Cause a Decrease in the Number of Pyramidal Neurons in the Rat Hippocampus
Kocacan, Suleyman Emre; Sefil, Fatih; Elibol, Ebru; Altunkaynak, Berrin Z.; Acar, Meryem Dilek; Bagirici, Faruk; Kaplan, Süleyman (Sci Printers & Publ Inc, 2016)OBJECTIVE: To investigate the effects of pentylenetetra-zole (PTZ) kindling on the number of pyramidal neurons in the rat hippocampus. STUDY DESIGN: Using unbiased stereology, we calculated total pyramidal neuron numbers ... -
Tutuşma modeli epilepside gap junction blokerlerinin antiepileptik ilaçlarla etkileşimi / Fatih Sefil; danışman Faruk Bağırıcı
Sefil, Fatih (Ondokuz Mayıs Üniversitesi, Tıp Fakultesi, 2010)…
