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Depression: reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress

Schmitz, C; Rhodes, ME; Bludau, M; Kaplan, S; Ong, P; Ueffing, I; Frye, CA (Nature Publishing Group, 2002)

It has been hypothesized that decreased neurogenesis in the dentate gyrus may be involved in mediating depressive disorders, which are 1.5-3 times more frequent in women than in men. Additionally, prenatal stress may ...