Yazar "Nar, Rukiye" için listeleme
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Effect of dexamethasone on unfolded protein response genes (MTJ1, Grp78, Grp94, CHOP, HMOX-1) in HEp2 cell line
Duzgun, Aynur; Bedir, Abdulkerim; Ozdemir, Tulay; Nar, Rukiye; Kilinc, Veli; Salis, Osman; Gulten, Sedat (Natl Inst Science Communication-Niscair, 2013)The endoplasmic reticulum (ER) is related to the various signal routes that are activated in unfolded protein response (UPR). The Grp78, Grp94, CHOP, MTJ1 and HMOX1 genes expressions demonstrate UPR activity. In this study, ... -
The effect of ouabain on mitochondrial DNA damage in HepG2 cell lines
Nar, Rukiye; Bedir, Abdulkerim; Alacam, Hasan; Kilinc, Veli; Avci, Bahattin; Salis, Osman; Gulten, Sedat (Springer, 2012)Our purpose in this study is to analyze mitochondrial DNA (mtDNA) lesion frequencies and mtDNA(4977) deletion in HepG2 cells to examine the effects of ouabain on mtDNA. HepG2 cells were treated with 0.75, 7.5, 75, and 750 ... -
Helicobacter Pylori Eradication Increases Telomere Length in Gastric Mucosa
Aslan, Rahmi; Bektas, Ahmet; Bedir, Abdulkerim; Alacam, Hasan; Aslan, Melek Suzer; Nar, Rukiye; Okuyucu, Ali (H G E Update Medical Publishing S A, 2013)Background/Aims: Our purpose in this study was to analyze telomere length and telomerase activity before and after eradication treatment in gastric mucosa in patients positive for H. pylori. Methodology: There were two ... -
HepG2 hücre kültürlerinde ouabainin mitokondriyal genom üzerindeki etkilerinin moleküler yöntemlerle araştırılması / Rukiye Nar ; danışman Abdulkerim Bedir
Nar, Rukiye (Ondokuz Mayıs Üniversitesi, Tıp Fakultesi, 2011)… -
Ouabain Targets the Unfolded Protein Response for Selective Killing of HepG2 Cells During Glucose Deprivation
Ozdemir, Tulay; Nar, Rukiye; Kilinc, Veli; Alacam, Hasan; Salis, Osman; Duzgun, Aynur; Bedir, Abdulkerim (Mary Ann Liebert Inc, 2012)Ouabain is a cardiotonic steroid and specific inhibitor of the Na+/K+-ATPase. The relationship between ouabain treatment and the unfolded protein response (UPR) in cells is not precisely understood. Therefore, we studied ... -
The relationship between epicardial fat thickness and gestational diabetes mellitus
Nar, Gokay; Inci, Sinan; Aksan, Gokhan; Unal, Oguz Kagan; Nar, Rukiye; Soylu, Korhan (Bmc, 2014)Aim: Gestational diabetes mellitus (GDM) is associated with cardiovascular diseases; however, the relationship between epicardial fat thickness (EFT) and GDM remains unclear. The present study evaluates and compares EFT ... -
The Relationships between Atrial Electromechanical Delay and CHA2DS2-VASc Score in Patients Diagnosed with Paroxysmal AF
Nar, Gokay; Inci, Sinan; Aksan, Gokhan; Soylu, Korhan; Demirelli, Selami; Nar, Rukiye (Wiley, 2015)AimThis study aims to evaluate the relationship between atrial electromechanical delay (AEMD) times and CHA2DS2-VASc scores in patients diagnosed with paroxysmal atrial fibrillation (PAF). Materials and MethodsThe study ... -
The telomere length of gastric mucosal samples and peripheral blood lymphocytes in patients who have undergone Billroth II distal gastrectomy
Ustaoglu, Muge; Bektas, Ahmet; Bedir, Abdulkerim; Bakir, Tulay; Duzgun, Aynur; Nar, Rukiye; Aslan, Rahmi (Termedia Publishing House Ltd, 2020)Introduction: Telomeres play an important role in maintaining chromosomal integrity. Functional loss of telomeres increases the risk of cancer by causing genomic instability. Telomere length abnormalities have been reported ...
