Yazar "Marangoz, C" için listeleme
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Calcium channel blocker flunarizine suppresses epileptiform activity induced by penicillin in rats
Bagirici, F; Gokce, FM; Demir, S; Marangoz, C (John Wiley & Sons Inc, 2001)Epilepsy is a neurological disorder that affects approximately 1% of the world population. It is accepted that calcium influx into the cell is the first step of epileptic neuronal events. In the present study, the effects ... -
A calcium channel blocker nicardipine protects neurons from zinc - Induced toxicity in rat hippocampus
Demir, S; Bagirici, F; Marangoz, C (John Wiley & Sons Ltd, 2002)The neurotoxicity is an important problem in medicine. The present study was designed to investigate the changes in pyramidal cell density of rat hippocampus after intracortical zinc sulphate (ZnSO4) and calcium channel ... -
Depressive effect of nicardipine on penicillin-induced epileptiform activity in rats
Bagirici, F; Gokce, FM; Marangoz, C (John Wiley & Sons Ltd, 1999)It is believed that calcium ions have very important role in the formation of epilepsy. Calcium ion flux into the cell leads to secretion of excitatory neurotransmitters. During epileptic seizures, routine balance of ... -
Do cochlear nuclei contribute to auditory lateralization? A stereological evaluation of neuron numbers
Agar, E; Korkmaz, A; Bosnak, M; Demir, S; Ayyildiz, M; Marangoz, C (Annals Publ Co, 1999)The aim of this study was to estimate the total number of cells in the subdivisions of the cochlear nucleus (CN) of the rat with unbiased stereological methods. The total number of neurons was determined in both the ventral ... -
The effects of calcium channel blocker, flunarizine on spinal reflexes in the cats
Gene, O; Demir, S; Tasci, N; Marangoz, C (Blackwell Science Ltd, 1998)… -
Effects of L-arginine on penicillin-induced epileptiform activity in rats
Marangoz, C; Bagirici, F (Japanese Pharmacological Soc, 2001)It has been suggested that nitric oxide (NO) is involved in the pathophysiology of epilepsy. Data are, however controversial because it is not clear whether NO has pro- or anticonvulsant effects. The aim of this study was ... -
Effects of nitric oxide on passive avoidance learning in rats
Yildirim, M; Marangoz, C (Taylor & Francis Ltd, 2004)To investigate the effects of nitric oxide (NO) on passive avoidance learning, L-NAME, D-NAME, and L-arginine were administered i.p. 30 min prior to learning trial; the effects of these substances were tested 24 h later ... -
Effects of the calcium channel blocker flunarizine on spinal reflexes in cats
Genc, O; Demir, S; Tasci, N; Kaptanoglu, B; Marangoz, C (Lippincott Williams & Wilkins, 1999)We have investigated the effects of the calcium channel blocker flunarizine on spinal monosynaptic reflexes in spinal cats. Flunarizine was administered locally into the spinal cord (10, 50, 100 mu M) and intraperitoneally ... -
Evidence That Sodium-Nitroprusside Possesses Anticonvulsant Effects Mediated Through Nitric-Oxide
Marangoz, C; Ayyildiz, M; Agar, E (Rapid Science Publishers, 1994)THE effect of sodium nitroprusside (SNP) on epileptiform activity elicited by administration of penicillin (500 units) into the somatomotor cortex was studied in anaesthetized rats. No epileptiform activity was observed ... -
L-arginine potentiates monosynaptic and polysynaptic spinal reflexes
Tasci, N; Ankarali, S; Demir, S; Canan, S; Marangoz, C (John Wiley & Sons Ltd, 2003)Nitric oxide (NO) is long been known to play a major role in a wide range of physiological functions as a neural messenger and a neurotransmitter. The aim of this study was to investigate the effects of NO precursor ... -
A NOS inhibitor aminoguanidine reduces zinc-induced neuron loss in rat hippocampus
Gokce, FM; Bagirici, F; Kaplan, S; Demir, S; Ayyildiz, M; Marangoz, C (John Wiley & Sons Ltd, 2003)There are many studies on zinc as a possible cause of neuronal hyperactivity and cell death. The present study was designed to investigate the changes in total pyramidal cell number of rat hippocampus after intracortical ... -
Numerical density of pyramidal neurons in the hippocampus of 4 and 20 week old male and female rats
Kaplan, S; Ragbetli, MC; Canan, S; Sahin, B; Marangoz, C (John Wiley & Sons Inc, 2003)A study designed to investigate how the cellular laterality in rostro-caudal direction changes due to age and sex was presented. It is a well-known fact that asymmetry is an important issue in understanding brain functions. ... -
Proconvulsant effects of central and peripheral administration of L-name on penicillin-induced epilepsy in rats
Bagirici, F; Marangoz, C (John Wiley & Sons Ltd, 2001)The effect of Nm-nitro L-arginine methyl ester (L-NAME) on penicillin-induced epileptiform activity was investigated in anaesthetized Wistar rats. Approximately 39.1 +/- 5.7 min after penicillin G (3 million U/kg, i.p.) ...
