Yazar "Kulcu, Canan" için listeleme
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Antimetastatic effect of fluvastatin on breast and hepatocellular carcinoma cells in relation to SGK1 and NDRG1 genes
Salis, Osman; Okuyucu, Ali; Bedir, Abdulkerim; Gor, Ufuk; Kulcu, Canan; Yenen, Eser; Kilic, Nermin (Sage Publications Ltd, 2016)Metastasis occurs due to migration of the cells from primary tumor toward other tissues by gaining invasive properties. Since metastatic invasion shows a strong resistance against conventional cancer treatments, the studies ... -
Cytotoxic Effect of Fluvastatin on MCF-7 Cells Possibly Through a Reduction of the mRNA Expression Levels of SGK1 and CAV1
Salis, Osman; Bedir, Abdulkerim; Gulten, Sedat; Okuyucu, Ali; Kulcu, Canan; Alacam, Hasan (Mary Ann Liebert, Inc, 2014)Fluvastatin (FLU) prevents the conversion of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) to mevalonic acid by inhibiting HMG-CoA reductase and decreases cholesterol level. Although the effects of FLU treatment on several ...
