Yazar "Kufrevioglu, O. Irfan" için listeleme
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Kinetic and docking studies of phenol-based inhibitors of carbonic anhydrase isoforms I, II, IX and XII evidence a new binding mode within the enzyme active site
Durdagi, Serdar; Senturk, Murat; Ekinci, Deniz; Balaydin, Halis Turker; Goksu, Suleyman; Kufrevioglu, O. Irfan; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2011)Carbonic anhydrases (CAs, EC 4.2.1.1) are inhibited by sulfonamides, inorganic anions, phenols, coumarins (acting as prodrugs) and polyamines. A novel class of CA inhibitors (CAIs), interacting with the CA isozymes I, II ... -
Purification and characterization of carbonic anhydrase from sheep kidney and effects of sulfonamides on enzyme activity
Demirdag, Ramazan; Comakli, Veysel; Senturk, Murat; Ekinci, Deniz; Kufrevioglu, O. Irfan; Supuran, Claudiu T. (Pergamon-Elsevier Science Ltd, 2013)Carbonic anhydrase (CA, EC: 4.2.1.1) was purified from sheep kidney by affinity chromatography on a Sepharose 4B-tyrosine-sulfanilamide column. By means of two consecutive procedures, the enzyme (sCA) was purified 227.61-fold ...
