Yazar "Koca, Suleyman Serdar" için listeleme
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Antiinflammatory and antioxidant effects of gemcitabine in collagen-induced arthritis model
Dagli, Adile Ferda; Karatas, Ahmet; Orhan, Cemal; Tuzcu, Mehmet; Ozgen, Metin; Sahin, Kazim; Koca, Suleyman Serdar (Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: Gemcitabine (GEM) has antiproliferative effects on lymphocytes, which are potent pathogenic actors of rheumatoid arthritis (RA). The aim of the study was to investigate the therapeutic potential of GEM on ... -
The IL-33 gene is related to increased susceptibility to systemic sclerosis
Koca, Suleyman Serdar; Pehlivan, Yavuz; Kara, Murat; Alibaz-Oner, Fatma; Oztuzcu, Serdar; Yilmaz, Neslihan; Onat, Ahmet Mesut (Springer Heidelberg, 2016)Systemic sclerosis (SSc) is a chronic inflammatory disease characterized by widespread fibrosis of the skin and several visceral organs. The pro-fibrotic potential of interleukin (IL)-33 has been demonstrated by in both ... -
Lapatinib Ameliorates Experimental Arthritis in Rats
Ozgen, Metin; Koca, Suleyman Serdar; Karatas, Ahmet; Dagli, Adile Ferda; Erman, Fazilet; Gundogdu, Baris; Isik, Ahmet (Springer/Plenum Publishers, 2015)Epidermal growth factor receptor (EGFR) and its ligands are commonly expressed by synovial cells. The aim of the present study was to detect the potential effect of lapatinib an inhibitor of EGFR tyrosine kinases on ... -
Low prevalence of obesity in Behcet's disease is associated with high obestatin level
Koca, Suleyman Serdar; Kara, Murat; Ozgen, Metin; Dayanan, Ramazan; Demir, Caner Feyzi; Aksoy, Kader; Isik, Ahmet (Aves, 2017)Objective: Chronic inflammatory diseases are associated with altered body composition. Ghrelin has anti-inflammatory effects, and its level is altered in obesity and inflammatory diseases. The aim of the study was to ... -
Paricalcitol inhibits the Wnt/beta-catenin signaling pathway and ameliorates experimentally induced arthritis
Yolbas, Servet; Yildirim, Ahmet; Tektemur, Ahmet; Celik, Zulfinaz Betul; Onalan Etem, Ebru; Ozercan, Ibrahim Hanifi; Koca, Suleyman Serdar (Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: The Wnt/beta-catenin pathway has important biological activities, including the differentiation of cells and joint formations. The aim of our study was to determine the effect of paricalcitol on experimentally ... -
Pemetrexed Ameliorates Experimental Arthritis in Rats
Karatas, Ahmet; Koca, Suleyman Serdar; Ozgen, Metin; Dagli, Adile Ferda; Erman, Fazilet; Sahin, Nuran; Isik, Ahmet (Springer/Plenum Publishers, 2015)Pemetrexed (PMTX) is an anti-folate drug as methotrexate. The purpose of this study was to assess the efficacy of PMTX on collagen-induced arthritis (CIA). Forty Wistar albino rats were randomized into four groups. Arthritis ... -
Sleep quality, sleeping postures, and sleeping equipment in patients with ankylosing spondylitis
Yolbas, Servet; Yildirim, Ahmet; Duzenci, Deccane; Gundogdu, Baris; Ozgen, Metin; Koca, Suleyman Serdar (Tubitak Scientific & Technical Research Council Turkey, 2017)Background/aim: Inflammatory back pain, spinal stiffness, and limited spinal mobility are characteristic features of ankylosing spondylitis (AS). Sleeping postures can affect and/or reflect sleeping disturbances. The aim ...