Yazar "Keles, Gonca Cayir" için listeleme
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Analysis of vitamin D receptor gene polymorphisms in patients with chronic periodontitis
Gunes, Sezgin; Sumer, A. Pinar; Keles, Gonca Cayir; Kara, Nurten; Koprulu, Hulya; Bagci, Hasan; Bek, Yuksel (Medknow Publications & Media Pvt Ltd, 2008)Background & objectives: Genetic polymorphisms in the vitamin D receptor (VDR) gene are related to bone mineral density, bone turnover, and diseases with bone loss. Alveolar bone loss is a key feature in periodontitis. The ... -
Analysis of YKL-40 Acute-Phase Protein and Interleukin-6 Levels in Periodontal Disease
Keles, Zeynep Pinar; Keles, Gonca Cayir; Avci, Bahattin; Cetinkaya, Burcu Ozkan; Emingil, Gulnur (Wiley, 2014)Background: YKL-40, a new acute-phase protein, is shown to be elevated in inflammatory diseases, such as rheumatoid arthritis, type 2 diabetes mellitus, and coronary artery diseases. However, there is no data indicating a ... -
Assessment of MMP-1, MMP-8 and TIMP-2 in experimental periodontitis treated with kaempferol
Balli, Umut; Cetinkaya, Burcu Ozkan; Keles, Gonca Cayir; Keles, Zeynep Pinar; Guler, Sevki; Sogut, Mehtap Unlu; Erisgin, Zuleyha (Korean Acad Periodontology, 2016)Purpose: The objective of this study was to investigate the effect of a dietary flavonoid, kaempferol, which has been shown to possess antiallergic, anti-inflammatory, anticarcinogenic, and antioxidant activities on the ... -
Assessment of Vascular Endothelial Growth Factor and Matrix Metalloproteinase-9 in the Periodontium of Rats Treated With Atorvastatin
Balli, Umut; Keles, Gonca Cayir; Cetinkaya, Burcu Ozkan; Mercan, Ugur; Ayas, Bulent; Erdogan, Deniz (Wiley, 2014)Background: The aim of this study is to examine, for the first time, the role of systemic and local atorvastatin application on periodontium using histomorphometric and immunohistochemical analysis during and after ... -
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis
Sumer, A. Pinar; Kara, Nurten; Keles, Gonca Cayir; Gunes, Sezgin; Koprulu, Hulya; Bagci, Hasan (Wiley, 2007)Background: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms ... -
Association of matrix metalloproteinase-9 promoter gene polymorphism with chronic periodontitis
Keles, Gonca Cayir; Gunes, Sezgin; Sumer, A. Pinar; Sumer, Mahmut; Kara, Nurten; Bagci, Hasan; Koprulu, Hulya (Wiley, 2006)Background: Matrix metalloproteinases (MMPs) are related to tissue destruction and remodeling events in periodontal diseases. A single nucleotide polymorphism in the promoter region of human MMP-9 gene is associated with ... -
Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population
Kara, Nurten; Keles, Gonca Cayir; Sumer, Pinar; Gunes, Sezgin Ozgur; Bagci, Hasan; Koprulu, Hulya; Bek, Yuksel (Taylor & Francis Ltd, 2007)Objectives. The etiology of periodontitis is related to the interaction between micro-organisms and host responses. Host modifving factors, such as genetic predisposition, may increase the severity of periodontitis. Recent ... -
Biochemical Analysis of Pentraxin 3 and Fibrinogen Levels in Experimental Periodontitis Model
Keles, Gonca Cayir; Balli, Umut; Cetinkaya, Burcu Ozkan; Ayas, Bulent; Findik, Arzu; Keles, Zeynep Pinar; Pamuk, Ferda (Hindawi Ltd, 2012)Objective. Pentraxin 3 (PTX3), newly discovered inflammation marker, is a member of acute-phase proteins. The hypothesis, synthesis of gingival tissue and serum PTX-3 increases in the experimental periodontitis model (with ... -
Comparison of mesenchymal stem cells and autogenous cortical bone graft in the treatment of class II furcation defects in dogs
Simsek, S. Burcak; Keles, Gonca Cayir; Baris, Sancar; Cetinkaya, Burcu Ozkan (Springer Heidelberg, 2012)The purpose of this study was to compare the effectiveness of mesenchymal stem cells (MSCs) with platelet-rich plasma (PRP) as scaffold and autogenous cortical bone (ACB) graft with and without PRP in the regenerative ... -
Comparison of platelet pellet and bioactive glass in periodontal regenerative therapy
Keles, Gonca Cayir; Cetinkaya, Burcu Ozkan; Albayrak, Davut; Koprulu, Hulya; Acikgoz, Gokhan (Taylor & Francis Ltd, 2006)Objective. In recent years, platelet-rich plasma combined with graft materials has been used for periodontal regeneration. The individual role of blood products with guided tissue regeneration in periodontal regenerative ... -
Comparison of platelet pellet with or without guided tissue regeneration in the treatment of class II furcation defects in dogs
Keles, Gonca Cayir; Cetinkaya, Burcu Ozkan; Baris, Sancar; Albayrak, Davut; Simsek, Selen Burcak (Springer Heidelberg, 2009)The purpose of this study was to compare histological effectiveness of platelet pellet (PP), which has higher platelet content than platelet-rich plasma, and the combination of PP/guided tissue regeneration (GTR) for class ... -
Comparison of the proliferative activity in gingival epithelium after surgical treatments of intrabony defects with bioactive glass and bioabsorbable membrane
Cetinkaya, Burcu Ozkan; Keles, Gonca Cayir; Ayas, Bulent; Aydin, Oguz; Kirtiloglu, Tugrul; Acikgoz, Gokhan (Springer Heidelberg, 2007)Guided tissue regeneration is based on preventing the more rapidly proliferating epithelium from growing into the periodontal defect after surgical procedures incorporating barrier membranes. The aim of this study was to ... -
The effect of cyclosporin A on alveolar bone in rats subjected to experimental periodontal disease
Cetinkaya, Burcu Ozkan; Acikgoz, Gokhan; Keles, Gonca Cayir; Ayas, Bulent; Korkmaz, Adnan (Taylor & Francis Inc, 2006)Cyclosporine A (CsA), broadly used in organ transplantation, may contribute to pathogenesis of osteoporosis. The aim of this study was to investigate the effects of CsA on alveolar bone in rats subjected or not to experimental ... -
Effects of Risedronate on Alveolar Bone Loss and Angiogenesis: A Stereologic Study in Rats
Cetinkaya, Burcu Ozkan; Keles, Gonca Cayir; Ayas, Bulent; Gurgor, Pinar (Wiley, 2008)Background: The present study was designed to evaluate the effects of risedronate, one of the most potent bisphosphonates, on alveolar bone resorption and angiogenesis in rats with experimental periodontitis to identify ... -
Effects of Tacrolimus and Nifedipine, Alone or in Combination, on Gingival Tissues
Pamuk, Ferda; Cetinkaya, Burcu Ozkan; Gulbahar, Mustafa Yavuz; Gacar, Ayhan; Keles, Gonca Cayir; Erisgin, Zuleyha; Arik, Nurol (Amer Acad Periodontology, 2013)Background: The aim of this study is to compare gingival changes induced by short-and long-term tacrolimus and nifedipine administration, alone or in combination, and evaluate the expression levels of tumor suppressor ... -
The expression of vascular endothelial growth factor in a rat model at destruction and healing stages of periodontal disease
Cetinkaya, Burcu Ozkan; Keles, Gonca Cayir; Ayas, Bulent; Sakallioglu, Elif Eser; Acikgoz, Gokhan (Wiley, 2007)Background: The major role of vascular endothelial growth factor (VEGF), an angiogenic mediator, in promoting the progression or the healing of periodontal disease is still unclear. The aim of this study was to evaluate ... -
Gingival levels of monocyte chemoattractant protein-1 (MCP-1) in diabetes mellitus and periodontitis: an experimental study in rats
Sakalhoglu, Elif Eser; Ayas, Buelent; Luetfloglu, Muege; Keles, Gonca Cayir; Acikgoez, Goekhan; Firath, Erhan (Springer Heidelberg, 2008)The objectives of this study were to investigate and compare the monocyte chemoattractant protein-1 (MCP-1) levels of gingival tissues in diabetes mellitus (DM) and periodontitis and to reveal the effects of MCP-1 on ... -
Histopathological and biochemical evaluation of paeoniflorin administration in an experimental periodontitis model
Gurkan, Cagla Gul; Keles, Gonca Cayir; Kurt, Sevda; Ciftci, Alper; Ayas, Bulent; Guler, Sevki; Cetinkaya, Burcu Ozkan (Nihon Univ, School Dentistry, 2019)The purpose of this study was to evaluate the effects of administered Paeoniflorin (Pae) on periodontal tissues within an experimental periodontitis model. Forty male Wistar rats were used in this study and experimental ... -
Levels of gingival tissue platelet activating factor after conventional and regenerative periodontal surgery
Keles, Gonca Cayir; Cetinkaya, Burcu Ozkan; Ayas, Bulent; Isildak, Ibrahim; Diraman, Emine; Koprulu, Hulya; Acikgoz, Gokhan (Springer Heidelberg, 2007)The hypothesis, a relationship between gingival tissue platelet activating factor (PAF) levels and healing after periodontal surgery, was tested by measuring PAF levels in gingival tissues collected from sites that had ... -
The levels of visceral adipose tissue-derived serpin, omentin-1 and tumor necrosis factor-alpha in the gingival crevicular fluid of obese patients following periodontal therapy
Balli, Umut; Dogan, Seyma Bozkurt; Dede, Figen Ongoz; Sertoglu, Erdim; Keles, Gonca Cayir (Nihon Univ, School Dentistry, 2016)The aim of this clinical study was to determine levels of visceral adipose tissue-derived serpin (vaspin), omentin-1, and tumor necrosis factor-alpha (TNF-alpha) in the gingival crevicular fluid (GCF) of obese and non-obese ...
