Yazar "Karakus, Nevin" için listeleme
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Association between sequence variations of the Mediterranean fever gene and fibromyalgia syndrome in a cohort of Turkish patients
Karakus, Nevin; Yigit, Serbulent; Inanir, Ahmet; Inanir, Sema; Toprak, Huriye; Okan, Sevil (Elsevier, 2012)Objective: Fibromyalgia syndrome (FMS) is a common chronic widespread pain syndrome mainly affecting women. Genetic risk factors are known to contribute to the etiology of the syndrome. Clinical features show that FMS and ... -
Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease
Karakus, Nevin; Yigit, Serbulent; Kalkan, Goknur; Rustemoglu, Aydin; Inanir, Ahmet; Gul, Ulker; Ates, Omer (Molecular Vision, 2012)Purpose: Behcet's disease (BD) is a multisystemic immunoinflammatory disorder characterized by mucocutaneous, ocular, vascular, and central nervous system manifestations. The common methylene tetrahydrofolate reductase ... -
Association of MEFV Gene Mutations With Rheumatoid Factor Levels in Patients With Rheumatoid Arthritis
Inanir, Ahmet; Yigit, Serbulent; Karakus, Nevin; Tekin, Saban; Rustemoglu, Aydin (Bmj Publishing Group, 2013)Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease primarily affecting the joints. Arthritis disorders are associated with mutations of the Mediterranean fever (MEFV) gene. This gene has already been ... -
Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population
Kaya, Emir F.; Karakus, Nevin; Ulusoy, Ali N.; Ozaslan, Cihangir; Kara, Nurten (Karger, 2016)Background: Breast cancer is the most common cancer among women. 1 in every 8 women in the United States have a lifetime risk of getting breast cancer. MTHFR is a key enzyme that regulates the folate metabolism which has ... -
A Case with Partial 9p Trisomy and Speech Impairment
Elbistan, Mehrnet; Tekcan, Akin; Tural, Sengul; Karakus, Nevin; Kara, Nurten (Derman Medical Publ, 2015)In this study, we aimed to discuss the relationships between his phenotypic anomalies and der(15), ish t(9; 15)(p12; q10) balanced reciprocal translocation entity that determined from 5 year old male child who referred to ... -
Common Mediterranean fever (MEFV) gene mutations associated with ankylosing spondylitis in Turkish population
Yigit, Serbulent; Inanir, Ahmet; Karakus, Nevin; Kesici, Esra; Bozkurt, Nihan (Hindawi Ltd, 2012)Ankylosing spondylitis (AS) is a common inflammatory rheumatic disease. Mediterranean fever (MEFV) gene, which has already been identified as being responsible for familial Mediterranean fever (FMF), is also a suspicious ... -
Cytogenetic Findings of Patients with Amenorrhea in Turkish Population: A Retrospective Study
Kara, Nurten; Tural, Sengul; Elbistan, Mehmet; Karakus, Nevin; Guven, Davut; Kocak, Idris (Kamla-Raj Enterprises, 2012)We performed a retrospective study, with the purpose of establishing the frequency of chromosomal anomalies in amenorrhea cases referred to our genetic laboratory from hospitals in the Middle Black Sea of Turkey. In this ... -
Effects of leptin and leptin receptor gene polymorphisms on lung cancer
Unsal, Meftun; Kara, Nurten; Karakus, Nevin; Tural, Sengul; Elbistan, Mehmet (Springer, 2014)Leptin (LEP), an adipocyte-derived cytokine, has been reported to participate in carcinogenesis. Elevated levels of systemic and pulmonary LEP are associated with diseases related to lung injury and lung cancer. The purpose ... -
Evaluation of CYP17A1 and LEP Gene Polymorphisms in Breast Cancer
Karakus, Nevin; Kara, Nurten; Ulusoy, Ali N.; Ozaslan, Cihangir; Tural, Sengul; Okan, Ismail (Karger, 2015)Background: Polymorphisms of estrogen synthesis- and adiposity-related genes can contribute to the development of breast cancer. The purpose of the current study was to analyze the association between CYP17A1 T27C (rs743572) ... -
Genotoxic Effects of Prenatal Exposure to Levetiracetam During Pregnancy on Rat Offsprings
Tural, Sengul; Tekcan, Akin; Elbistan, Mehmet; Karakus, Nevin; Ozyurek, Hamit; Kara, Nurten (Int Inst Anticancer Research, 2015)Levetiracetam is a new-generation antiepileptic drug initially approved as an adjunctive treatment for patients with refractory partial seizures and is now also used as a monotherapy. The aim of this study was to evaluate ... -
Influence of PON1 gene polymorphisms (rs662 and rs854560) on the chronicity of HBV infection
Karakus, Nevin; Duygu, Fazilet; Coskun, Umut Say; Atay, Ayfer; Yigit, Serbulent (Elsevier, 2020)Hepatitis B is a major health problem in Turkey as it is all over the world. Therefore, it is noteworthy to understand the genetic background of hepatitis B virus (HBV)-infection. In order to investigate the effect of the ... -
Lack of association between prohibitin 3 ' untranslated region C -> T polymorphism and breast cancer in a Turkish population
Karakus, Nevin; Kara, Nurten; Ulusoy, Ali Naki (Mary Ann Liebert Inc, 2008)The 30 untranslated region (3 ' UTR) of the prohibitin gene has a positive effect on arresting cell proliferation between G1 and S phases and inhibits DNA synthesis. A C-to-T transition within this region creates a variant ... -
P53 Codon 72 and HER2 Codon 655 Polymorphisms in Turkish Breast Cancer Patients
Kara, Nurten; Karakus, Nevin; Ulusoy, Ali Naki; Ozaslan, Cihangir; Gungor, Bulent; Bagci, Hasan (Mary Ann Liebert Inc, 2010)The polymorphisms in codon 72 of the tumor suppressor protein p53 (P53) gene and codon 655 of the human epidermal growth factor receptor 2 (HER2) gene have been suggested to play roles in most cancers. The purpose of this ... -
Significance of MEFV gene R202Q polymorphism in Turkish familial Mediterranean fever patients
Yigit, Serbulent; Karakus, Nevin; Tasliyurt, Turker; Kaya, Suheyla Uzun; Bozkurt, Nihan; Kisacik, Bunyamin (Elsevier Science Bv, 2012)Objective: Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and inflammation in the peritoneum, synovium, or pleura, accompanied by pain. The disease is ... -
Significant association of interleukin-4 gene intron 3 VNTR polymorphism with susceptibility to knee osteoarthritis
Yigit, Serbulent; Inanir, Ahmet; Tekcan, Akin; Tural, Ercan; Ozturk, Gokhan Tuna; Kismali, Gorkem; Karakus, Nevin (Elsevier, 2014)Objective: Interleukin-4 (IL-4) is a strong chondroprotective cytokine and polymorphisms within this gene may be a risk factor for osteoarthritis (OA). We aimed to investigate genotype and allele frequencies of IL-4 gene ... -
Tumor Necrosis Factor Alpha and Beta and Interferon Gamma Gene Polymorphisms in Turkish Breast Cancer Patients
Karakus, Nevin; Kara, Nurten; Ulusoy, Ali Naki; Ozaslan, Cihangir; Bek, Yuksel (Mary Ann Liebert, Inc, 2011)Cytokine genes are important for researching cancer predisposition to cancers that elicit anti-tumor immune response. In this study, we investigated the association between breast cancer and tumor necrosis factor alpha ...
