Yazar "Kara, Nurten" için listeleme
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Ailesel dengeli resiprokal translokasyon t(9;11)(p12;p11.2)’un üreme performansına etkisi
Amaç: Bu çalışmada, sekiz yıldır infertil, dört IUI (Intrauterin Inseminasyon) denemesinin başarısız, IVF (In Vitro Fertilizasyon) denemesinin ikincisinde başarılı olan fakat 8 haftalıkken gebelik kaybı yaşayan bir çift ... -
Analysis of vitamin D receptor gene polymorphisms in patients with chronic periodontitis
Gunes, Sezgin; Sumer, A. Pinar; Keles, Gonca Cayir; Kara, Nurten; Koprulu, Hulya; Bagci, Hasan; Bek, Yuksel (Medknow Publications & Media Pvt Ltd, 2008)Background & objectives: Genetic polymorphisms in the vitamin D receptor (VDR) gene are related to bone mineral density, bone turnover, and diseases with bone loss. Alveolar bone loss is a key feature in periodontitis. The ... -
Association between osteoporosis and polymorphisms of the bone Gla protein, estrogen receptor 1, collagen 1-A1 and calcitonin receptor genes in Turkish postmenopausal women
Tural, Sengul; Kara, Nurten; Alayli, Gamze; Tomak, Leman (Elsevier Science Bv, 2013)In this study, we have investigated the association between osteoporosis and osteocalcin (BGLAP) -298 C>T, estrogen receptor 1 (ER1) 397 T>C, collagen type1 alpha 1 (Col1A1) 2046 G>T and calcitonin receptor (CALCR) 1340 ... -
Association between osteoporosis and polymorphisms of the IL-10 and TGF-beta genes in Turkish postmenopausal women
Tural, Sengul; Alayli, Gamze; Kara, Nurten; Tander, Berna; Bilgici, Ayhan; Kuru, Omer (Elsevier Science Inc, 2013)Osteoporosis is a multifactorial disease in which genetic determinants are modulated by hormonal, environmental and nutritional factors. The balance between bone resorption and bone formation seems to be regulated by a ... -
Association of eNOS gene polymorphism (Glu298Asp) with psoriasis
Senturk, Nilgun; Kara, Nurten; Aydin, Fatma; Gunes, Sezgin; Yuksel, Esra Pancar; Bagci, Hasan; Turanli, Ahmet Yasar (Elsevier Ireland Ltd, 2006)… -
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis
Sumer, A. Pinar; Kara, Nurten; Keles, Gonca Cayir; Gunes, Sezgin; Koprulu, Hulya; Bagci, Hasan (Wiley, 2007)Background: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms ... -
Association of matrix metalloproteinase-9 promoter gene polymorphism with chronic periodontitis
Keles, Gonca Cayir; Gunes, Sezgin; Sumer, A. Pinar; Sumer, Mahmut; Kara, Nurten; Bagci, Hasan; Koprulu, Hulya (Wiley, 2006)Background: Matrix metalloproteinases (MMPs) are related to tissue destruction and remodeling events in periodontal diseases. A single nucleotide polymorphism in the promoter region of human MMP-9 gene is associated with ... -
Association of serotonin 2A receptor and lack of association of CYP1A2 gene polymorphism with tardive dyskinesia in a Turkish population
Boke, Omer; Gunes, Sezgin; Kara, Nurten; Aker, Servet; Sahin, Ahmet Rifat; Basar, Yildiz; Bagci, Hasan (Mary Ann Liebert, Inc, 2007)The aim of this study was to investigate the possible association of serotonin 2A receptor gene (HTR2A) - 1438 G/A polymorphism and CYP1A2 gene 163C/ A polymorphism with tardive dyskinesia (TD) in a Turkish population. A ... -
Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population
Kaya, Emir F.; Karakus, Nevin; Ulusoy, Ali N.; Ozaslan, Cihangir; Kara, Nurten (Karger, 2016)Background: Breast cancer is the most common cancer among women. 1 in every 8 women in the United States have a lifetime risk of getting breast cancer. MTHFR is a key enzyme that regulates the folate metabolism which has ... -
Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population
Kara, Nurten; Keles, Gonca Cayir; Sumer, Pinar; Gunes, Sezgin Ozgur; Bagci, Hasan; Koprulu, Hulya; Bek, Yuksel (Taylor & Francis Ltd, 2007)Objectives. The etiology of periodontitis is related to the interaction between micro-organisms and host responses. Host modifving factors, such as genetic predisposition, may increase the severity of periodontitis. Recent ... -
Association of transforming growth factor beta 1 gene polymorphism with rheumatoid arthritis in a Turkish population
Alayli, Gamze; Kara, Nurten; Tander, Berna; Canturk, Ferhan; Gunes, Sezgin; Bagci, Hasan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)Objective: Cytokine genes play important role, in the pathogenesis of rheumatoid arthritis (RA). In RA, the plasma and synovial fluid levels of transforming growth factor beta 1 (TGF beta 1) have been shown to be raised. ... -
A case with Down syndrome presenting 21q22q translocation: Differential diagnosis
Guenes, Sezgin; Kara, Nurten; Guenal, Nazlihan; Kuecuekoeduek, Suekrue; Oekten, Guelsen; Tural, Senguel; Taskin, Emre (Ortadogu Ad Pres & Publ Co, 2007)Robertsonian translocations (ROBs) are the most common chromosomal rearrangemets. ROBs are whole-arm rearrangements between the acrocentric chromosomes chromosomes 13, 14, 15, 21, and 22. ROBs can be classified into 2 ... -
A Case with Partial 9p Trisomy and Speech Impairment
Elbistan, Mehrnet; Tekcan, Akin; Tural, Sengul; Karakus, Nevin; Kara, Nurten (Derman Medical Publ, 2015)In this study, we aimed to discuss the relationships between his phenotypic anomalies and der(15), ish t(9; 15)(p12; q10) balanced reciprocal translocation entity that determined from 5 year old male child who referred to ... -
Chromosomal microarray analysis of patients with Duane retraction syndrome
Niyaz, Leyla; Tural, Sengul; Yucel, Ozlem Eski; Can, Ertugrul; Ariturk, Nursen; Celik, Zulfinaz B.; Kara, Nurten (Springer, 2019)Purpose Duane retraction syndrome (DS) is a rare congenital strabismus with genetic heterogeneity. The genetic causes of DS are not always of monogenic origin; various chromosomal copy number variations (CNVs) have also ... -
The combined QF-PCR and cytogenetic approach in prenatal diagnosis
Tekcan, Akin; Tural, Sengul; Elbistan, Mehmet; Kara, Nurten; Guven, Davut; Kocak, Idris (Springer, 2014)In this study, the importance of quantitative fluorescence polymerase chain reaction (QF-PCR) aneuploidy diagnosis test which provides earlier and easier results were discussed. The cell cultures and DNA isolations were ... -
Cytogenetic Findings of Patients with Amenorrhea in Turkish Population: A Retrospective Study
Kara, Nurten; Tural, Sengul; Elbistan, Mehmet; Karakus, Nevin; Guven, Davut; Kocak, Idris (Kamla-Raj Enterprises, 2012)We performed a retrospective study, with the purpose of establishing the frequency of chromosomal anomalies in amenorrhea cases referred to our genetic laboratory from hospitals in the Middle Black Sea of Turkey. In this ... -
DEFB4A Promoter Polymorphism Is Associated with Chronic Periodontitis: A Case-Control Study
Kurt-Bayrakdar, Sevda; Ozturk, Ayla; Kara, Nurten (Mary Ann Liebert, Inc, 2020)Background: Human beta-defensin-2 is an antimicrobial weapon peptide with antibiotic properties secreted by the oral cavity to protect the host against microbial attack. The interindividual differences of defensin expression ... -
The effect of L-glutamine on mucosal healing in experimental colitis is superior to short-chain fatty acids
Kaya, Ekrem; Ceylan, Alper; Kara, Nurten; Gueven, Hakan; Yildiz, Levent (Turkish Soc Gastroenterology, 2007)Background/aims: The effects of short-chain fatty acids and glutamine on diseased colonic mucosa, such as in inflammatory bowel disease, are not well described. The aim of this study was to investigate the role of L-glutamine ... -
Effects of leptin and leptin receptor gene polymorphisms on lung cancer
Unsal, Meftun; Kara, Nurten; Karakus, Nevin; Tural, Sengul; Elbistan, Mehmet (Springer, 2014)Leptin (LEP), an adipocyte-derived cytokine, has been reported to participate in carcinogenesis. Elevated levels of systemic and pulmonary LEP are associated with diseases related to lung injury and lung cancer. The purpose ... -
An epileptic case with mosaic ring chromosome 6 and 6q terminal deletion
Kara, Nurten; Okten, Gulsen; Gunes, Sezgin Ozgur; Saglam, Yaman; Tasdemir, Haydar Ali; Pinarli, Ferda Alparslan (Elsevier Science Bv, 2008)Ring chromosomes are rare chromosome disorders that arise usually de novo. Children with ring chromosome 6 have a wide range of intellectual functioning and congenital anomalies. We report an epileptic case of a 10-year-old ...
