Yazar "Jahanshahi, Ali" için listeleme
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Deep Brain Stimulation of the Rat Subthalamic Nucleus Induced Inhibition of Median Raphe Serotonergic and Dopaminergic Neurotransmission
Kocabicak, Ersoy; Jahanshahi, Ali; Schonfeld, Lisa; Hescham, Sarah-Anna; Temel, Yasin; Tan, Sonny (Turkish Neurosurgical Soc, 2015)AIM: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) relieves motor dysfunction in advanced Parkinson's disease (PD). However, STN DBS treated patients can experience unpleasant and debilitating psychiatric ... -
Does Probe's Eye Subthalamic Nucleus Length on T2W MRI Correspond with Microelectrode Recording in Patients with Deep Brain Stimulation for Advanced Parkinson's Disease?
Kocabicak, Ersoy; Aygun, Dursun; Ozaydin, Ilkay; Jahanshahi, Ali; Tan, Sonny K. H.; Onar, Musa; Temel, Yasin (Turkish Neurosurgical Soc, 2013)AIM: Subthalamic nucleus (STN) deep brain stimulation (DBS) has become a well-accepted treatment for patients with advanced Parkinson's disease (PD). During surgical planning for DBS, the length of the STN is taken into ... -
Electrical stimulation of the motor cortex enhances progenitor cell migration in the adult rat brain
Jahanshahi, Ali; Schonfeld, Lisa; Janssen, Marcus L. F.; Hescham, Sarah; Kocabicak, Ersoy; Steinbusch, Harry W. M.; Temel, Yasin (Springer, 2013)Clinical and preclinical investigations suggest that epidural stimulation of the motor cortex (MC) can improve stroke-induced neurological deficits. The mechanisms involved in stimulation-induced recovery are not well ... -
Hyperdopaminergic Status in Experimental Huntington Disease
Jahanshahi, Ali; Vlamings, Rinske; Kaya, Ahmet Hilmi; Lim, Lee Wei; Janssen, Marcus L. F.; Tan, Sonny; Temel, Yasin (Oxford Univ Press Inc, 2010)Huntington disease has been linked to increased dopaminergic neurotransmission in the striatum, and clinical studies have demonstrated that the associated chorea can be treated with dopamine antagonist or dopamine-depleting ... -
Transgenic Rat Models of Huntington's Disease
Carreira, Joao Casaca; Jahanshahi, Ali; Zeef, Dagmar; Kocabicak, Ersoy; Vlamings, Rinske; von Hoersten, Stephan; Temel, Yasin (Springer International Publishing Ag, 2015)Several animal models for Huntington's disease (HD) have been created in order to investigate mechanisms of disease, and to evaluate the potency of novel therapies. Here, we describe the characteristics of the two transgenic ... -
Volumetric analysis of the subthalamic and red nuclei based on magnetic resonance imaging in patients with Parkinson's disease
Camlidag, Ilkay; Kocabicak, Ersoy; Sahin, Bunyamin; Jahanshahi, Ali; Incesu, Lutfi; Aygun, Dursun; Belet, Umit (Taylor & Francis Ltd, 2014)Parkinson's disease (PD) is associated with degeneration of the dopaminergic neurons in the substantia nigra. The subthalamic nucleus (STN) plays a pivotal role in the pathogenesis. However, there is not much known about ...