Yazar "Guvenc, Tolga" için listeleme
-
Aromatase expression in the cerebellum of the dog infected with canine distemper virus
Yarim, Murat; Gulbahar, Mustafa Yavuz; Guvenc, Tolga; Karahan, Siyami; Harada, Nobuhiro; Kabak, Yonca Betil; Karayigit, Mehmet Onder (Schluetersche Verlagsgesellschaft Mbh & Co Kg, 2010)Aromatase is the enzyme that catalyzes the biosynthesis of estrogens. It is implicated in neuroprotection. The present study investigated aromatase expression in the cerebellum of dogs infected with canine distemper virus ... -
Biological Significance of the Over-Expression of Hsp70 and Alpha B-Crystallin in Rat Substantia Nigra Exposed To Different Doses of Permethrin
Guvenc, Dilek; Kabak, Yonca Betil; Atmaca, Enes; Aksoy, Abdurrahman; Guvenc, Tolga (Inst Medical Research & Occupational Health, 2013)The aim of this study was to investigate the possible role of the Heat Shock Protein 70 (HSP70) and Alpha B-crystallin (alpha BC) in the substantia nigra of rats exposed to permethrin at different doses on the apoptotic ... -
Characterization of local immune response against lungworms in naturally infected sheep
Gulbahar, M. Yavuz; Davis, William C.; Yarim, Murat; Guvenc, Tolga; Umur, Sinasi; Kabak, Yonca B.; Beyhan, Y. Emre (Elsevier Science Bv, 2009)This study describes the immunohistochemical and histochemical phenotypes of inflammatory cells in sheep lungs infected with lungworms. A total of 20 naturally infected sheep lungs were used. Protostrongylus spp., Muellerius ... -
Does Resveratrol Have a Protective Effect on Tympanosclerosis Formation in Experimentally Induced Otitis Media?
Kurnaz, Senem Cengel; Aksoy, Ahmet; Guvenc, Dilek; Guvenc, Tolga; Aksoy, Abdurrahman (Aves, 2014)OBJECTIVE: To evaluate the effects of resveratrol on tympanosclerosis in an experimental rat model by otomicroscopic, histopathological, and immunohistochemical examinations, and measurement of malondialdehyde levels. ... -
Dose- and Time-dependent Effects of Permethrin on HepG2 Cells: Cell Survival, Lipid Peroxidation and Antioxidant Defence System
Guvenc, Dilek; Gulbahar, M. Yavuz; Yavuz, Oguzhan; Guvenc, Tolga (Kafkas Univ, Veteriner Fakultesi Dergisi, 2020)There is very limited knowledge about in vitro hepatotoxicity of permethrin concerning dose and duration even though humans and nontargeted beings are exposed. In this study, three different doses of permethrin (1 mu M, ... -
The effect of curcumin on lung injuries in a rat model induced by aspirating gastrointestinal decontamination agents
Gunaydin, Mithat; Guzel, Aygul; Guzel, Ahmet; Alacam, Hasan; Salis, Osman; Murat, Naci; Guvenc, Tolga (W B Saunders Co-Elsevier Inc, 2012)Background: Aspiration is one of the most feared complications of gastrointestinal decontamination procedures with nonabsorbed polyethylene glycol (PEG) solution and activated charcoal (AC). We aimed to investigate the ... -
The Effects of Dexamethasone and L-NAME on Acute Lung Injury in Rats with Lung Contusion
Kozan, Ahmet; Kilic, Nermin; Alacam, Hasan; Guzel, Ahmet; Guvenc, Tolga; Acikgoz, Mehmet (Springer/Plenum Publishers, 2016)The therapeutic efficiency of an anti-inflammatory agent, dexamethasone (DXM), and a nitric oxide synthase (NOS) inhibitor, Nitro-L-arginine methyl ester (L-NAME), in lung tissue injury after lung contusion was investigated. ... -
Effects of polyglecaprone 25, silk and catgut suture materials on oral mucosa wound healing in diabetic rats: An evaluation of nitric oxide dynamics
Yilmaz, Nergiz; Inal, Samet; Muglali, Mehtap; Guvenc, Tolga; Bas, Burcu (Medicina Oral S L, 2010)Objectives: The purpose of this study is to investigate the effects of monocryl (Polyglecaprone 25), silk and catgut suture materials on wound healing in diabetic rats and to evaluate NO (nitric oxide) dynamics. Study ... -
Efficacy of tigecycline/colistin combination in a pneumonia model caused by extensively drug-resistant Acinetobacter baumannii
Yilmaz, Esmeray Mutlu; Sunbul, Mustafa; Aksoy, Abdurrahman; Yilmaz, Hava; Guney, Akif Koray; Guvenc, Tolga (Elsevier, 2012)Due to increasing drug resistance, available antimicrobial options are limited in the treatment of Acinetobacter baumannii infections. Particularly in cases caused by extensively drug-resistant (XDR) A. baumannii, combination ... -
Evaluation of apoptotic cell death on liver and kidney tissues following administration of levetiracetam during prenatal period
Tekcan, Akin; Tural, Sengul; Elbistan, Mehmet; Guvenc, Tolga; Ayas, Bulent; Kara, Nurten (Taylor & Francis Ltd, 2017)Objective: Levetiracetam is a new generation antiepileptic drug used in treatment of patients with epilepsy and has adverse effects on different tissues. We aimed to evaluate the apoptotic effects of levetiracetam exposure ... -
Evaluation of changes in monoamine levels and apoptosis induced by cyfluthrin in rats
Guvenc, Dilek; Aksoy, Abdurrahman; Gacar, Ayhan; Atmaca, Enes; Das, Kursad Y.; Guvenc, Tolga (Oxford Univ Press, 2014)The aim of this study was to evaluate monoamine and mitochondrial cytochrome c levels and lipid peroxidation in adult male rats treated with cyfluthrin (14 mg kg(-1) dose; approximately 1/10 of the LD50 value) for 14 days. ... -
The expressions of HSP70 and alpha B-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs
Gulbahar, Mustafa Yavuz; Kabak, Yonca Betil; Karayigit, Mehmet Onder; Yarim, Murat; Guvenc, Tolga; Parlak, Unal (Korean Soc Veterinary Science, 2011)This study describes the expression of heat shock protein70 (HSP70) and alpha-basic-crystallin (alpha-BC) and their association with apoptosis and some related adaptor proteins in the pathogenesis of foot-and-mouth disease ... -
Immunohistochemical Comparison of Indermil With Traditional Suture Materials in Dental Surgery
Muglali, Mehtap; Yilmaz, Nergiz; Inal, Samet; Guvenc, Tolga (Lippincott Williams & Wilkins, 2011)The aim of this experimental study was to evaluate the effects of indermil on the closure of oral mucosa wounds in comparison with conventional sutures by investigating interleukin 1 beta (IL-1 beta) and tumor necrosis ... -
Immunohistochemical distribution of alpha B-crystallin in the cerebellum of dogs infected with canine distemper virus
Guvenc, Tolga; Yarim, Murat; Gulbahar, Mustafa Yavuz; Kabak, Yonca B. (Akademiai Kiado, 2008)The cerebella of 12 dogs infected with canine distemper virus (CDV) and those of three normal dogs were examined. The avidin-biotin-peroxidase complex technique was used to detect alpha B-crystallin (alpha B-c) immunoreactivity ... -
Inducible nitric oxide synthase expression in cerebellum of dogs naturally infected with canine distemper virus
Yarim, Murat; Karayigit, M. Onder; Gacar, Ayhan; Kabak, Yonca B.; Gulbahar, M. Yavuz; Guvenc, Tolga; Sozmen, Mahmut (Ankara Univ Press, 2015)The aim of this study is to investigate of inducible nitric oxide synthase (iNOS) and nitrotyrosine (NT) expression in the cerebellum of dogs naturally infected with canine distemper virus (CDV), a disease characterized ... -
Infliximab attenuates activated charcoal and polyethylene glycol aspiration-induced lung injury in rats
Guzel, Aygul; Gunaydin, Mithat; Guzel, Ahmet; Alacam, Hasan; Murat, Naci; Gacar, Ayhan; Guvenc, Tolga (Taylor & Francis Inc, 2012)Aspiration is a serious complication of gastrointestinal (GI) decontamination procedure. Studies have shown that tumor necrosis factor-alpha (TNF-alpha) blockers have beneficial effects on lung injury. Therefore, the authors ... -
Mammary fibroadenoma in a lamb
Gulbahar, M. Yavuz; Guvenc, Tolga; Yarim, Murat; Kabak, Yonca B.; Sozgen, Yuksel (Korean Soc Veterinary Science, 2007)A fibroadenoma was diagnosed in the left udder of a 3-month-old female Chios lamb. No recurrence was observed after surgery. Grossly, the tumor had a whitish-gray lobular appearance, and the lobules were interlaced with ... -
A Novel Tissue Prefabrication Model in Rabbit Using Polyacrylamide Cryogel Scaffolds
Ozturk, Nuray; Demirtas, Yener; Karayigir, Onder; Egri, Sinan; Kibar, Guenes; Guvenc, Tolga; Karacalar, Ahmet (Ieee, 2009)Tissue engineering is one of the important approaches for both soft and hard tissue repair and reconstruction. In this approach, scaffolds having highly and open pore structures which would allow an efficient vascularization ... -
Oviduct adenocarcinoma with a possible magnal area origin in a budgerigar (Melopsittacus undulates)
Yarim, Murat; Gulbahar, Mustafa Yavuz; Ozak, Ahmet; Guvenc, Tolga (Ankara Univ Press, 2011)A female 8-year-old budgerigar was presented a slowly progressive growth at abdominal region. The bird died during surgery. On necropsy, the tumoral mass composed of vesicular/cystic soap bubble-like polypoid masses were ... -
Reactions of connective tissue to amalgam, intermediate restorative material, mineral trioxide aggregate, and mineral trioxide aggregate mixed with chlorhexidine
Sumer, Mahmut; Muglali, Mehtap; Bodrumlu, Emre; Guvenc, Tolga (Elsevier Science Inc, 2006)The aim of this study was to histopathologically examine the biocompatibility of the high-copper amalgam, intermediate restorative material (IRM), mineral trioxide aggregate (MTA), and MTA mixed with chlorhexidine (CHX). ...
