Yazar "Gultekin, Mehmet Serdar" için listeleme
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A novel and one-pot synthesis of new 1-tosyl pyrrol-2-one derivatives and analysis of carbonic anhydrase inhibitory potencies
Alp, Cemalettin; Ekinci, Deniz; Gultekin, Mehmet Serdar; Senturk, Murat; Sahin, Ertan; Kufrevioglu, Omer Irfan (Pergamon-Elsevier Science Ltd, 2010)Here we propose a novel one-pot synthesis of new tosyl-pyrrole derivatives. By means of the new developed method, pyrrole derivatives were synthesized at room temperature in a single step, and a useful method is proposed ... -
Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II
Alp, Cemalettin; Maresca, Alfonso; Alp, Nurdan Alcan; Gultekin, Mehmet Serdar; Ekinci, Deniz; Scozzafava, Andrea; Supuran, Claudiu T. (Taylor & Francis Ltd, 2013)Carbonic anhydrase inhibitors of primary sulfonamide type, RSO2NH2, have clinical applications as diuretics, antiglaucoma, antiepileptic, antiobesity and antitumor drugs. Here we investigated inhibition of two human cytosolic ...