Yazar "Gepdiremen, A" için listeleme
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Acute anti-inflammatory activity of four saponins isolated from ivy: alpha-hederin, hederasaponin-C, hederacolchiside-E and hederacolchiside-F in carrageenan-induced rat paw edema
Gepdiremen, A; Mshvildadze, V; Suleyman, H; Elias, R (Elsevier Gmbh, Urban & Fischer Verlag, 2005)The anti-inflammatory potential of alpha-hederin (monodesmoside) and hederasaponin-C from Hedera helix, and hederacolchisides-E and -F (bidesmosides) from H. colchica was investigated in carrageenan-induced acute paw edema ... -
The antioxidant activity of a triterpenoid glycoside isolated from the berries of Hedera colchica: 3-O-(beta-D-glucopyranosyl)-hederagenin
Gulcin, I; Mshvildadze, V; Gepdiremen, A; Elias, R (Wiley, 2006)The antioxidant activity of a triterpenoid glycoside [3-O-(beta-D-glucopyranosyl)-hederagenin; OGH] isolated from the berries of Hedera colchica, an ivy species endemic in Georgia, was investigated. The antioxidant properties ... -
Antiradical and antioxidant activity of total anthocyanins from Perilla pankinensis decne
Gulcin, I; Berashvili, D; Gepdiremen, A (Elsevier Ireland Ltd, 2005)The purpose of this work comprise the assessment of the antioxidant activity of total anthocyanins from Perilla pankinensis samples (TAPP) by different analytical methods: 1,1-diphenyl-2-picrylhydrazyl (DPPH center dot) ... -
The effects of ruthenium red, dantrolene and nimodipine, alone or in combination, in NMDA induced neurotoxicity of cerebellar granular cell culture of rats
Duzenli, S; Bakuridze, K; Gepdiremen, A (Pergamon-Elsevier Science Ltd, 2005). In the present study, we used the L-type calcium channel blocker nimodipine, the endoplasmic reticulum (ER) calcium release blocker dantrolene and the calcium transport blocker in mitochondria ruthenium red (RuR), in ... -
L-carnitine protects against glutamate- and kainic acid-induced neurotoxicity in cerebellar granular cell culture of rats
Tastekin, A; Gepdiremen, A; Ors, R; Buyukokuroglu, ME; Halici, Z (Elsevier Science Bv, 2005)Glutamate mediated intracellular calcium accumulation and free radical generation are thought to be major mechanisms that contribute to cell death in hypoxic-ischemic brain injury. For this reason, various glutamate receptor ... -
Radioprotective effects of melatonin on radiation-induced cataract
Karslioglu, I; Ertekin, MV; Taysi, S; Kocer, I; Sezen, O; Gepdiremen, A; Bakan, N (Oxford Univ Press, 2005)One of the mechanisms proposed to explain tens opacification is the oxidation of crystallins, either by radiation or reactive oxygen species (ROS). It has been shown that melatonin has both an anti-peroxidative effect on ... -
Reactive blue prevented caffeine-induced neurotoxicity by an independent mechanism from intracellular calcium currents in cell culture from auditory cortex of rats
Ucuncu, H; Bakuridze, K; Duzenli, S; Halici, Z; Buyukokuroglu, ME; Gepdiremen, A (Taylor & Francis Ltd, 2005)Neurotoxicity induced by caffeine ill auditory-neuron cultures was studied ill rat pups. For possible protective effect. reactive blue (RB) alone and ill combination with dantrolene were tested in subsequent doses. RB was ... -
Three haplotypes associated with CYP2A6 phenotypes in Caucasians
Haberl, M; Anwald, B; Klein, K; Weil, R; Fuss, C; Gepdiremen, A; Wojnowski, L (Lippincott Williams & Wilkins, 2005)The human cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several xenobiotic compounds of clinical or toxicological importance. We aimed to identify genetic variants and major CYP2A6 haplotypes associated with CYP2A6 ...