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Association of Abl interactor 2, ABI2, with platelet/lymphocyte ratio in patients with renal cell carcinoma: A pilot study
Ergun, Sercan; Gunes, Sezgin; Buyukalpelli, Recep; Aydin, Oguz (Wiley, 9999)There are many unknown aspects of the pathogenesis of renal cell carcinoma (RCC). The aim of the current study was to define new RCC-related genes and measure their associations with RCC and clinical parameters, especially ... -
Glutamate transporter SLC1A1 is associated with clear cell renal cell carcinoma
Ergun, Sercan; Gunes, Sezgin; Buyukalpelli, Recep; Aydin, Oguz (Tubitak Scientific & Technical Research Council Turkey, 2019)Background/aim: This study aimed to comparatively analyze the expression levels of the SLC1A1 gene in renal specimens from tumors and adjacent healthy kidney tissues of patients with clear cell renal cell carcinoma (ccRCC). ... -
miRNAs as Potential Treatment Targets and Treatment Options in Cancer
Petrovic, Nina; Ergun, Sercan (Adis Int Ltd, 2018)Standard cancer therapies for solid malignancies, such as chemotherapy and radiotherapy, are not target specific against cancer cells and are often not fully efficacious. Chemotherapy and radiotherapy may cause side effects, ... -
Significance of miR-15a-5p and CNKSR3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer
Ergun, Sercan; Guney, Serkan; Temiz, Ebru; Petrovic, Nina; Gunes, Sezgin (Bentham Science Publ Ltd, 2018)Background: In recent years, targeted cancer treatment methods at various molecular levels have been developed for Non-Small Cell Lung Cancer (NSCLC), one of two major subtypes of lung cancer. miRNA-based clinical trials ... -
Tr-KIT/c-KIT ratio in renal cell carcinoma
Ergun, Sercan; Altay, Diler Us; Gunes, Sezgin; Buyukalpelli, Recep; Karahan, Suleyman Caner; Tomak, Leman; Abur, Ummet (Springer, 2019)Truncated KIT (tr-KIT) is an alternative variant of c-KIT protein. Previous studies have clearly documented that c-KIT was associated with various oncogenic processes in RCC. However, the biological significance of tr-KIT ...