Yazar "Elbistan, Mehmet" için listeleme
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The combined QF-PCR and cytogenetic approach in prenatal diagnosis
Tekcan, Akin; Tural, Sengul; Elbistan, Mehmet; Kara, Nurten; Guven, Davut; Kocak, Idris (Springer, 2014)In this study, the importance of quantitative fluorescence polymerase chain reaction (QF-PCR) aneuploidy diagnosis test which provides earlier and easier results were discussed. The cell cultures and DNA isolations were ... -
Cytogenetic Findings of Patients with Amenorrhea in Turkish Population: A Retrospective Study
Kara, Nurten; Tural, Sengul; Elbistan, Mehmet; Karakus, Nevin; Guven, Davut; Kocak, Idris (Kamla-Raj Enterprises, 2012)We performed a retrospective study, with the purpose of establishing the frequency of chromosomal anomalies in amenorrhea cases referred to our genetic laboratory from hospitals in the Middle Black Sea of Turkey. In this ... -
DPP-4 inhibitörü antidiyabetik vildagliptin ile sitagliptinin genotoksisite ve sitotoksisite açısından araştırılması / Ceren Börçek Kasurka ; danışman Mehmet Elbistan.
Kasurka, Ceren Börçek (Ondokuz Mayıs Üniversitesi, Sağlık Bilimleri Enstitüsü, 2017)… -
Düşük materyallerinde kromozomların subtelomerik bölgelerinin MLPA yöntemiyle araştırılması / Akın Tekcan ; Danışman Mehmet Elbistan
Tekcan, Akın (Ondokuz Mayıs Üniversitesi, Sağlık Bilimleri Enstitüsü, 2008)… -
Effects of leptin and leptin receptor gene polymorphisms on lung cancer
Unsal, Meftun; Kara, Nurten; Karakus, Nevin; Tural, Sengul; Elbistan, Mehmet (Springer, 2014)Leptin (LEP), an adipocyte-derived cytokine, has been reported to participate in carcinogenesis. Elevated levels of systemic and pulmonary LEP are associated with diseases related to lung injury and lung cancer. The purpose ... -
Effects of subtelomeric copy number variations in miscarriages
Tekcan, Akin; Elbistan, Mehmet; Tural, Sengul; Cetinkaya, Mehmet Bilge (Taylor & Francis Ltd, 2015)Purpose: This study was performed on miscarriage samples for chromosome analysis to detect copy number variations (CNVs) related to subtelomeric regions, and with these results we aimed to adapt multiplex ligation-dependent ... -
Evaluation of apoptotic cell death on liver and kidney tissues following administration of levetiracetam during prenatal period
Tekcan, Akin; Tural, Sengul; Elbistan, Mehmet; Guvenc, Tolga; Ayas, Bulent; Kara, Nurten (Taylor & Francis Ltd, 2017)Objective: Levetiracetam is a new generation antiepileptic drug used in treatment of patients with epilepsy and has adverse effects on different tissues. We aimed to evaluate the apoptotic effects of levetiracetam exposure ... -
FMR1 gene mutation screening by TP-PCR in patients with premature ovarian failure and fragile-X
Tural, Sengul; Tekcan, Akin; Kara, Nurten; Elbistan, Mehmet; Guven, Davut; Tasdemir, Haydar Ali (Informa Healthcare, 2015)CGG repeat expansion in the FMR1 gene is associated with fragile X syndrome, fragile X-associated tremor/ ataxia syndrome and fragile X-associated primary ovarian insufficiency. In this study, FMR1 gene mutation screening ... -
Genotoxic Effects of Prenatal Exposure to Levetiracetam During Pregnancy on Rat Offsprings
Tural, Sengul; Tekcan, Akin; Elbistan, Mehmet; Karakus, Nevin; Ozyurek, Hamit; Kara, Nurten (Int Inst Anticancer Research, 2015)Levetiracetam is a new-generation antiepileptic drug initially approved as an adjunctive treatment for patients with refractory partial seizures and is now also used as a monotherapy. The aim of this study was to evaluate ... -
In vitro cytogenetic assessment and comparison of vildagliptin and sitagliptin
Kasurka, Ceren Borcek; Elbistan, Mehmet; Atmaca, Aysegul; Sekeroglu, Zulal Atli (Springer, 2019)Vildagliptin and sitagliptin are commonly used antidiabetic drugs. Chromosomal aberration (CA), sister chromatid exchange (SCE) and cytokinesis-block micronucleus (CBMN) assays were employed to assess and compare cytotoxic ... -
Meme kanserli hastalarda tedavi öncesi, tedavi süreci ve remisyon döneminde kardeş kromatid değişimlerinin araştırılması / Akın Tekcan; Danışman Mehmet Elbistan
Tekcan, Akın (Ondokuz Mayıs Üniversitesi, Sağlık Bilimleri Enstitüsü, 2008)Bu çalışmada; meme kanserli 25 kadın hastadan ve sigara kullanmayan 22 kontrol grubu kadından hazırlanan periferik kan kültürlerinde kardeş kromatid değişim sıklıkları araştırılmıştır. Hasta grubun kardeş kromatid değişim ... -
Perisentrik inversiyon 9 gözlenen olguların değerlendirilmesi
İnversiyon 9, genellikle fenotipik özellik göstermeyen önemli bir yapısal düzensizlik olarak görülmektedir. Çalışma, inversiyon 9’un etkilerini ve önemini değerlendirmek amacıyla laboratuvarımızda saptanan 62 inversiyon 9 ... -
PPAR-alpha and PPARGC1A gene variants have strong effects on aerobic performance of Turkish elite endurance athletes
Tural, Ercan; Kara, Nurten; Agaoglu, Seydi Ahmet; Elbistan, Mehmet; Tasmektepligil, Mehmet Yalcin; Imamoglu, Osman (Springer, 2014)The aim of this study was to investigate the effect of PPAR-alpha intron 7G > C and PPARGC1A gene Gly482Ser polymorphisms on aerobic performance of elite level endurance athletes. This study was carried out on 170 inviduals ... -
Samsun'un Sivaslılar, Sakarlı ve Avut mahallelerinde akraba evliliklerinin sıklığı ve toplum sağlığına etkileri / Çılga Özmete ; Danışman Mehmet Elbistan.
Özmete, Çılga (Ondokuz Mayıs Üniversitesi, Sağlık Bilimleri Enstitüsü, 2019)… -
Sister chromatid exchanges in breast cancer patients who underwent chemotherapy
Tekcan, Akin; Elbistan, Mehmet; Ulusoy, Ali Naki (Japanese Soc Toxicological Sciences, 2012)The study aimed to determine the effects of cytostatic and genotoxic drugs used to treat breast cancer on sister chromatid exchange (SCE). SCE values were examined in 25 female patients with breast cancer in pre-treatment, ... -
Şizofrenik hastalarda dermatoglifik analizler / Nur Sözübür; Danışman Mehmet Elbistan.
Sözübir, Nur (Ondokuz Mayıs Üniversitesi, Sağlık Bilimleri Enstitüsü, 2004)Sinir sistemindeki gelişme ve fonksiyon bozukluklarının prenatal teşhisinde önemli antropometrik özelliklerin başında dermatoglifikler gelmektedir.Dermatoglifiklerin değişmezliği dikkate alınarak yapılan bu çalışmada ...
