Browsing by Author "Bostanci, M. Omer"
Now showing items 1-12 of 12
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Anticonvulsive effects of carbenoxolone on penicillin-induced epileptiform activity: An in vivo study
Bostanci, M. Omer; Bagirici, Faruk (Pergamon-Elsevier Science Ltd, 2007)Epilepsy is an important problem in neurological disorders. Recent studies claimed that gap junctions have a critical role in epileptic neuronal events. The aim of present study is to investigate the effects of gap junction ... -
Anticonvulsive effects of nimodipine on penicillin-induced epileptiform activity
Bagirici, Faruk; Bostanci, M. Omer (Nencki Inst Experimental Biology, 2006)The common features of all types of epilepsy are synchronized and uncontrolled discharges of nerve cell assemblies. It is believed that calcium ions play an important role in the generation of epileptic activity. Excessive ... -
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity the role of L-type calcium channels in iron-induced neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Informa Healthcare, 2013)Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ... -
The Effect of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole on the Cell Death Induced by Zinc Administration in the Brain of Rats
Gokce, M. Fatih; Bagirici, Faruk; Demir, Serif; Bostanci, M. Omer; Guven, Aysel (Tubitak Scientific & Technical Research Council Turkey, 2009)Aim: To evaluate the effect of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-Nl) on hippocampal cell loss induced by zinc hemisulfate salt (ZnSO4-7H2O) treatment. Materials and Methods: Rats were ... -
The Effects of Nitric Oxide Synthesis Inhibitors on Iron-Induced Nigral Neurotoxicity
Bostanci, M. Omer; Bas, Orhan; Bagirici, Faruk (Springer Tokyo, 2009)… -
The effects of octanol on penicillin induced epileptiform activity in rats: An in vivo study
Bostanci, M. Omer; Bagirici, Faiuk (Elsevier Science Bv, 2006)The common features of all types of epilepsy are the synchronized and uncontrolled discharges of nerve cell assemblies. The reason for the pathologically synchronized discharges of the neuron is not exactly known yet. ... -
Inhibition of neuronal nitric oxide synthase prevents iron-induced cerebellar Purkinje cell loss in the rat
Gulturk, Sefa; Kozan, Ramazan; Bostanci, M. Omer; Sefil, Fatih; Bagirici, Faruk (Nencki Inst Experimental Biology, 2008)Iron plays an important role in maintaining normal. brain function. However, in many neurodegenerative diseases abnormal iron accumulation in specific brain regions has been consistently reported. In this study, we ... -
Neuroprotection by 7-nitroindazole against iron-induced hippocampal neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Springer/Plenum Publishers, 2007)(1) Iron plays an important role in maintaining normal brain function. In some neurodegenerative disorders including Parkinson's and Alzheimer's disease, iron levels rise in the brain. It is known that higher iron levels ... -
Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity
Bostanci, M. Omer; Bagirici, Faruk (Pergamon-Elsevier Science Ltd, 2008)Iron is a commonly used metal to induce neuronal hyperactivity and oxidative stress. Iron levels rise in the brain in some neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. A body of evidence indicates ... -
Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
Bostanci, M. Omer; Bagirici, Faruk; Bas, Orhan (Taylor & Francis Ltd, 2008)In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ...
