Yazar "Beydemir, Sukru" için listeleme
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An Alternative Purification Method for Human Serum Paraoxonase 1 and its Interactions with Sulfonamides
Ekinci, Deniz; Senturk, Murat; Beydemir, Sukru; Kufrevioglu, Omar Irfan; Supuran, Claudiu T. (Wiley-Blackwell, 2010)Paraoxonase 1 (PON1), a high-density lipoprotein (HDL)-associated esterase, is known to mediate antioxidant and antiatherogenic properties. Purification of PON1 has been challenging for a long time. Here, we report a novel ... -
Increasing stocking density causes inhibition of metabolic-antioxidant enzymes and elevates mRNA levels of heat shock protein 70 in rainbow trout
Aksakal, Ercument; Ekinci, Deniz; Erdogan, Orhan; Beydemir, Sukru; Alim, Zuhal; Ceyhun, Saltuk Bugrahan (Elsevier, 2011)The objective of this study was to determine the effects of stocking density on the activity of glucose 6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD) and glutathione reductase (GR) enzymes in ... -
Influence of Cobalt and Zinc Exposure on mRNA Expression Profiles of Metallothionein and Cytocrome P450 in Rainbow Trout
Ceyhun, Saltuk Bugrahan; Aksakal, Ercument; Ekinci, Deniz; Erdogan, Orhan; Beydemir, Sukru (Humana Press Inc, 2011)The present research aims to evaluate the effects of cobalt and zinc exposure of rainbow trout (Oncorhynchus mykiss) on metallothioneins and cytocrome P450. Mature rainbow trouts were exposed to 10 mg/L CoCl2.6H(2)O and 1 ... -
Paraoxonase-1, an organophosphate detoxifier and cardioprotective enzyme, is inhibited by anesthetics: An in vitro and in vivo insight
Senturk, Murat; Ekinci, Deniz; Alici, Haci Ahmet; Beydemir, Sukru (Academic Press Inc Elsevier Science, 2011)Paraoxonase-1 enzyme (PON1) is important in metabolism as an organophosphate (OP) hydrolyser, hydrolyses aromatic carboxyl esters, such as phenyl acetate, and is involved in drug and xenobiotic metabolism. Moreover, it ... -
Protective role of L-carnitine supplementation against exhaustive exercise induced oxidative stress in rats
Siktar, Elif; Ekinci, Deniz; Siktar, Erdinc; Beydemir, Sukru; Gulcin, Ilhami; Gunay, Mehmet (Elsevier Science Bv, 2011)The objective of this study was to investigate temperature dependent effects of oral L-carnitine supplementation on exhaustive exercise induced oxidative damage in rats. 42 male Sprague Dawley rats were randomly divided ... -
Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols including natural products
Balaydin, Halis Turker; Soyut, Hakan; Ekinci, Deniz; Goksu, Suleyman; Beydemir, Sukru; Menzek, Abdullah; Sahin, Ertan (Taylor & Francis Ltd, 2012)(2-Bromo-3,4-dimethoxyphenyl) (3,4-dimethoxyphenyl) methanone (10) and its derivatives with Br, one dibromide and isomeric three tribromides, were synthesized. Demethylation of these compounds afforded a series of new ...