Yazar "Arslan, Mehmet Alper" için listeleme
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Effects of aging on the male reproductive system
Gunes, Sezgin; Hekim, Gulgez Neslihan Taskurt; Arslan, Mehmet Alper; Asci, Ramazan (Springer/Plenum Publishers, 2016)The study aims to discuss the effects of aging on the male reproductive system. A systematic review was performed using PubMed from 1980 to 2014. Aging is a natural process comprising of irreversible changes due to a myriad ... -
Investigating the relationship between BRCA1 and BRCA2 genes methylation profile and sperm DNA fragmentation in infertile men
Kabartan, Emel; Gunes, Sezgin; Arslan, Mehmet Alper; Asci, Ramazan (Wiley, 2019)The purpose of the study was to investigate whether the promoter methylation status of BRCA1 and BRCA2 DNA repair genes is associated with sperm DNA fragmentation (sDF) in infertile men with oligoasthenoteratozoospermia ... -
The role of epigenetics in idiopathic male infertility
Gunes, Sezgin; Arslan, Mehmet Alper; Hekim, Gulgez Neslihan Taskurt; Asci, Ramazan (Springer/Plenum Publishers, 2016)Infertility is a complex disorder with multiple genetic and environmental causes. Although some specific mutations have been identified, other factors responsible for sperm defects remain largely unknown. Despite considerable ... -
Smoking-induced genetic and epigenetic alterations in infertile men
Gunes, Sezgin; Mahmutoglu, Asli Metin; Arslan, Mehmet Alper; Henkel, Ralf (Wiley, 2018)Male fertility rates have shown a progressive decrease in both developing and industrialised countries in the past 50years. Clinical and epidemiological studies have demonstrated controversial results about the harmful ...