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Comparison between Flexible Collagen and Vein Conduits Used for Size-Discrepant Nerve Repair: An Experimental Study in Rats
Demir, Ahmet; Simsek, Tekin; Acar, Murat; Aktas, Abit; Vlamings, Rinkse; Ayyildiz, Mustafa; Kaplan, Süleyman (Thieme Medical Publ Inc, 2014)Primary nerve repair is the gold standard in nerve reconstruction. When primary repair is not possible for injured nerves, conduit-assisted repair methods are frequently used. As conduits, autologous vein segments or ... -
The Effect of Melatonin and Platelet Gel on Sciatic Nerve Repair: An Electrophysiological and Stereological Study
Kaplan, Süleyman; Piskin, Ahmet; Ayyildiz, Mustafa; Aktas, Abit; Koksal, Bulent; Ulkay, Muzaffer Basak; Geuna, Stefano (Wiley, 2011)Nerve regeneration after surgical reconstruction is far from optimal, and thus effective strategies for improving the outcome of nerve repair are being sought. In this experiment, we verified if postoperative intraperitoneal ... -
The effect of prenatal exposure of a non-steroidal anti-inflammatory drug on the optic nerve of female rats: a stereological, histological, and electron microscopic study
Kaplan, Süleyman; Esrefoglu, Mukaddes; Aktas, Abit; Gul, Mehmet; Onger, Mehmet Emin; Altunkaynak, M. Eyup; Ragbetli, Murat Cetin (Taylor & Francis Ltd, 2013)Objective: Non-steroidal anti-inflammatory drugs (NSAIDs) can have adverse effects for in both mother and fetus following administration during the prenatal period. If given during pregnancy, diclofenac sodium (DS), an ... -
Platelet Gel Does Not Improve Peripheral Nerve Regeneration: An Electrophysiological, Stereological, and Electron Microscopic Study
Piskin, Ahmet; Kaplan, Süleyman; Aktas, Abit; Ayyildiz, Mustafa; Raimondo, Stefania; Alic, Taner; Geuna, Stefano (Wiley, 2009)Although use of platelet gel (PG) for promoting tissue regeneration is a popular approach because of its capacity to accelerate tissue regeneration, to our knowledge, its effects on peripheral nerve have still not been ... -
Prenatal exposure of diclofenac sodium affects morphology but not axon number of the median nerve of rats
Ayranci, Ebru; Altunkaynak, Berrin Zuhal; Aktas, Abit; Ragbetli, Murat C.; Kaplan, Süleyman (Termedia Publishing House Ltd, 2013)The present study examined the effect of DS exposure on median nerve development in rats during prenatal life. Pregnant female rats were divided into three groups: a control group, a saline group and a DS group. Offspring ... -
Prenatal exposure to a non-steroidal anti-inflammatory drug or saline solution impairs sciatic nerve morphology: a stereological and histological study
Canan, Sinan; Aktas, Abit; Ulkay, M. Basak; Colakoglu, Serdar; Ragbetli, Murat Cetin; Ayyildiz, Mustafa; Kaplan, Süleyman (Pergamon-Elsevier Science Ltd, 2008)The toxic effect of non-steroidal anti-inflammatory drugs (NSAIDs) during development has been widely investigated. While it has been shown that these drugs impair central nervous development and compromise the neural ...