Publication:
Temperature Effect on Binding Affinity and Stoichiometry Between Some Steroids and Human Serum Albumin

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dc.authorscopusid36509110300
dc.authorscopusid6603524165
dc.contributor.authorÖzdemir, S.
dc.contributor.authorBi̇Çer, E.
dc.date.accessioned2020-06-21T13:33:59Z
dc.date.available2020-06-21T13:33:59Z
dc.date.issued2016
dc.departmentOndokuz Mayıs Üniversitesien_US
dc.department-temp[Özdemir] Serkan, Ondokuz Mayis University Faculty of Science and Arts, Samsun, Turkey; [Bi̇Çer] Ender, Ondokuz Mayis University Faculty of Science and Arts, Samsun, Turkeyen_US
dc.description.abstractThe temperature dependence of the interactions between some steroids (fusidic acid, ouabain and ethynodioldiacetate) and human serum albumin (HSA) at physiological pH (7.4) were studied systematically by square-wave voltammetry. Also, these interactions were proven by means of UV-Vis. absorption spectroscopy and FT-IR spectroscopy techniques. The interaction parameters (binding constants and stoichiometries) at temperature range of 297.5-312.5 K were determined from electrochemical data. It is worthy that the temperature has played a positive role on the interactions of fusidic acid with HSA; however it has negative effective on the interaction parameters of HSA with ouabain or ethynodioldiacetate. © 2016, Sociedad Chilena de Quimica. All rights reserved.en_US
dc.identifier.doi10.4067/S0717-97072016000100013
dc.identifier.endpage2815en_US
dc.identifier.issn0717-9324
dc.identifier.issn0717-9707
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84977074376
dc.identifier.scopusqualityQ2
dc.identifier.startpage2809en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-97072016000100013
dc.identifier.volume61en_US
dc.identifier.wosWOS:000378145500013
dc.identifier.wosqualityQ3
dc.language.isoenen_US
dc.publisherSociedad Chilena de Químicaen_US
dc.relation.ispartofJournal of the Chilean Chemical Societyen_US
dc.relation.journalJournal of the Chilean Chemical Societyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBinding Affinityen_US
dc.subjectHuman Serum Albuminen_US
dc.subjectSteroidsen_US
dc.subjectTemperature Effecten_US
dc.subjectVoltammetryen_US
dc.titleTemperature Effect on Binding Affinity and Stoichiometry Between Some Steroids and Human Serum Albuminen_US
dc.typeArticleen_US
dspace.entity.typePublication

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