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The Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Rats

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dc.contributor.authorAlkis, Mehmet Esref
dc.contributor.authorKavak, Servet
dc.contributor.authorSayir, Fuat
dc.contributor.authorHim, Aydin
dc.contributor.authorIDALKIS, Mehmet Esref/0000-0002-3321-2873
dc.date.accessioned2020-06-21T13:34:13Z
dc.date.available2020-06-21T13:34:13Z
dc.date.issued2016
dc.departmentOMÜen_US
dc.department-temp[Alkis, Mehmet Esref] Mus Alparslan Univ, Vocat Coll Tech Programmes, Mus, Turkey -- [Kavak, Servet] Mugla Sitki Kocman Univ, Fac Med, Dept Biophys, Mugla, Turkey -- [Sayir, Fuat] Yuzuncu Yil Univ, Fac Med, Dept Thorac Surg, Van, Turkey -- [Him, Aydin] Ondokuz Mayis Univ, Sch Med, Dept Biophys, Samsun, Turkey --en_US
dc.description.abstractThe aim of this study was to investigate the effect of axotomy and crush-related degeneration on the electrical activities of diaphragm muscle strips of experimental rats. In the present study, twenty-one male Wistar-albino rats were used and divided into three groups. The animals in the first group were not crushed or axotomized and served as controls. Phrenic nerves of the rats in the second and third groups were crushed or axotomized in the diaphragm muscle. Resting membrane potential (RMP) was decreased significantly in both crush and axotomy of diaphragm muscle strips of experimental rats (p < 0.05). Depolarization time (T (DEP)) and half-repolarization (1/2 RT) time were significantly prolonged in crush and axotomy rats (p < 0.05). Crushing or axotomizing the phrenic nerves may produce electrical activities in the diaphragm muscle of the rat by depolarization time and half-repolarization time prolonged in crush and axotomy rats.en_US
dc.description.sponsorshipYuzuncu Yil UniversityYuzuncu Yil Universityen_US
dc.description.sponsorshipThis work was supported by the Yuzuncu Yil University Research Projects Department. We thank Dr. Nurettin Cengiz and Hava Bektas.en_US
dc.identifier.doi10.1007/s12013-015-0708-3
dc.identifier.endpage34en_US
dc.identifier.issn1085-9195
dc.identifier.issn1559-0283
dc.identifier.issue1en_US
dc.identifier.pmid26972299
dc.identifier.startpage29en_US
dc.identifier.urihttps://doi.org/10.1007/s12013-015-0708-3
dc.identifier.urihttps://hdl.handle.net/20.500.12712/13470
dc.identifier.volume74en_US
dc.identifier.wosWOS:000372472400005
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.journalCell Biochemistry and Biophysicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectro-Biophysicsen_US
dc.subjectPhrenic Nervesen_US
dc.subjectDiaphragm Muscleen_US
dc.subjectRatsen_US
dc.titleThe Effects of Phrenic Nerve Degeneration by Axotomy and Crush on the Electrical Activities of Diaphragm Muscles of Ratsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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