2-Amino-4-(2-naphthyl)thiophene-3-carbonitrile

Abstract

A new type of thiophene derivative with potential pharmacological activity, viz. 2-amino-4-(2-naphthalyl) thiophene-3carbonitrile, C15H10N2S, has been prepared and studied by NMR and single-crystal X- ray diffraction techniques. The molecule contains two different groups, naphthalene and thiophene, which are nearly perpendicular to one another. In the crystal structure, a hydrogen bond, with a D center dot center dot center dot A distance of 3.033 (3) angstrom, is present between the amino substituent and the carbonitrile N atom of a symmetry-related molecule. The crystal structure also includes one C-H center dot center dot center dot pi interaction.