dc.contributor.author | Ayan, Ali Kemal | |
dc.contributor.author | Radusiene, Jolita | |
dc.contributor.author | Cirak, Cueneyt | |
dc.contributor.author | Ivanauskas, Liudas | |
dc.contributor.author | Janulis, Valdimaras | |
dc.date.accessioned | 2020-06-21T14:55:04Z | |
dc.date.available | 2020-06-21T14:55:04Z | |
dc.date.issued | 2009 | |
dc.identifier.issn | 1388-0209 | |
dc.identifier.issn | 1744-5116 | |
dc.identifier.uri | https://doi.org/10.1080/13880200902942436 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12712/18488 | |
dc.description | WOS: 000270847000004 | en_US |
dc.description.abstract | The genus Hypericum (Guttiferae) is a source of biologically active secondary metabolites, notably hyperforin, hypericins and various phenolics. In the present study the presence of the phloroglucinol derivative hyperforin, the naphthodianthrones hypericin and pseuclohypericin, the phenylpropane chlorogenic acid and the flavonoids such as rutin, hyperoside, apigenin-7-O-glucoside, kaempferol, quercitrin, quercetin and amentoflavone were investigated in two Turkish species of Hypericum, namely, Hypericum scabrum L. and Hypericum bupleuroides Gris. The aerial parts representing a total of 30 individuals were collected at full flowering and dissected into floral, leaf and stem tissues. After being dried at room temperature, the plant materials were assayed for secondary metabolite concentrations by HPLC. All of the secondary metabolites examined were detected in both species at various levels depending on plant tissue except for hyperforin which was not accumulated in Hypericum scabrum. The presence of hyperforin and the phenolic compounds examined in both species were reported by us for the first time. | en_US |
dc.description.sponsorship | Scientific Foundation of Kaunas University of Medicine | en_US |
dc.description.sponsorship | The chemical evaluation was supported by the Scientific Foundation of Kaunas University of Medicine. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.relation.isversionof | 10.1080/13880200902942436 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Hypericin | en_US |
dc.subject | pseudohypericin | en_US |
dc.subject | hyperforin | en_US |
dc.subject | phenolic constituents | en_US |
dc.subject | morphogenetic variation | en_US |
dc.subject | secondary chemistry | en_US |
dc.title | Secondary metabolites of Hypericum scabrum and Hypericum bupleuroides | en_US |
dc.type | article | en_US |
dc.contributor.department | OMÜ | en_US |
dc.identifier.volume | 47 | en_US |
dc.identifier.issue | 9 | en_US |
dc.identifier.startpage | 847 | en_US |
dc.identifier.endpage | 853 | en_US |
dc.relation.journal | Pharmaceutical Biology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |