3R*,4R*)-1-(4-Chlorophenyl)-4-[2-hydroxy-3-(morpholinomethyl) phenyl]-3-phenoxyazetidin-2-one

Abstract

The beta-lactam ring of the title compound, C26H25ClN2O4, is nearly planar (r.m.s. deviation = 0.025 angstrom) and the morpholine ring adopts a chair conformation. The mean plane of the beta-lactam ring makes dihedral angles of 21.6 (4), 84.4 (4) and 33.7 (4)degrees with the two benzene rings and the phenyl ring, respectively. The conformation of the title compound is stabilized by intramolecular C-H center dot center dot center dot O and O-H center dot center dot center dot N interactions. The crystal structure features C-H center dot center dot center dot pi and aromatic pi-pi stacking interactions [centroid-centroid distances = 3.684 (4) and 3.883 (4) angstrom].