Possible effects of endometriosis-related immune events on reproductive function

Abstract

Purpose To examine possible effects of endometriosis-related immune events on reproductive function. Methods The synthesis and review of the relevant current literature in English language. Results The endometriosis-related immune events may have a negative impact on almost all components of the reproductive function including fallopian tube function, oocyte quality, sperm function, fertilization, embryo quality, endometrial receptivity, implantation and placentation. Conclusions An important portion of the cases of infertility or miscarriage seen in women with endometriosis may be due to some immunological alterations associated with endometriosis.