Ameliorative effects of paricalcitol against 1800-MHz mobile phone radiation-induced skin damage in rats

Abstract

This study aimed to evaluate the protective role of paricalcitol, a vitamin D analog, against hazardous effects of 1800MHz radiofrequency (RF) radiation on the skin of male Wistar albino rats exposed one h/day for 4weeks. The maximum specific absorption rate was calculated as 0.0042W/kg. Superoxide dismutase and catalase activity, collagen bundle thickness, breaking force, energy, and stress were decreased, while malondialdehyde level and mast cell number were increased. The exposure to 1800-MHz RF radiation caused a reduction in skin biomechanical quality through oxidative stress and mast cell activation. The administration of paricalcitol caused a significant improvement.