Investigation of the 8-hydroxy-2 '-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli

Tarih
2014Yazar
Ciftci, GulayUral, Kerem
Aysul, Nuran
Cenesiz, Sena
Guzel, Murat
Pekmezci, Didem
Sogut, Mehtap Unlu
Üst veri
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Oxidative stress was defined as corruption of balance between oxidant-antioxidant states in favor of oxidants. In this study, it was aimed to determine oxidative stress in naturally infected dogs with Babesia vogeli. The 8-hydroxy-2'-deoxyguanosine (8-OHdG), nitric oxide (NO) and total antioxidant capacity (TAC) levels in the sera were analyzed by ELISA. 8-OHdG levels increased in B. vogeli infected dogs compared to control group (P < 0.05). Also, NO levels increased while TOC levels decreased in B. vogeli infected dogs but these variations were not found as statistically important (P > 0.05). (C) 2014 Elsevier B.V. All rights reserved.