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Toplam kayıt 19, listelenen: 1-10
Effects of diclofenac sodium on the hippocampus of rats with acute subdural hematoma: histological, stereological, and molecular approach
(Termedia Publishing House Ltd, 2016)
This study was aimed at evaluating the potential effects of acute subdural hematoma (ASDH) and diclofenac sodium (DS) therapy following ASDH on the rat hippocampus. Twenty-four male Sprague Dawley rats were used and divided ...
The effects of different doses of diclofenac sodium on newborn rat hippocampus exposed during the third trimester
(Scientific Technical Research Council Turkey-Tubitak, 2020)
The main aim of the present study was to examine the neurotoxic effects of prenatal exposure to varying doses of diclofenac sodium (DS) on the rat hippocampus. Twenty-eight Wistar albino adult female rats weighing 280-300 ...
Effects of prenatal PPAR- agonist rosiglitazone exposure on rat hippocampus development in a time-dependent manner: A stereological and histopathological study
(Sage Publications Ltd, 2018)
Rosiglitazone is in the thiazolidinedione class of drugs used in the treatment of type 2 diabetes mellitus. It works as an insulin sensitizer by binding to the peroxisome proliferator-activated receptor gamma. We investigated ...
Blocking of L-type calcium channels protects hippocampal and nigral neurons against iron neurotoxicity the role of L-type calcium channels in iron-induced neurotoxicity
(Informa Healthcare, 2013)
Iron plays an important role in maintaining normal brain function. However, iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders such as ...
Effects of diabetes and ovariectomy on rat hippocampus (A biochemical and stereological study)
(Taylor & Francis Ltd, 2012)
Oxidative stress is one of the main reasons of both menopause and diabetes. So, it plays crucial role in the pathogeneses of that condition and disease. Therefore, the objective of the present study was to investigate the ...
Effects of postnatal formaldehyde exposure on pyramidal cell number, volume of cell layer in hippocampus and hemisphere in the rat: A stereological study
(Elsevier Science Bv, 2007)
The purpose of the present study was to determine whether exposure of neonatal rats to formaldehyde (FA) had either early or delayed effects on the numbers of pyramidal cells in the cornu ammonis (CA) of the hippocampus. ...
The Effect of Neuronal Nitric Oxide Synthase Inhibitor 7-Nitroindazole on the Cell Death Induced by Zinc Administration in the Brain of Rats
(Tubitak Scientific & Technical Research Council Turkey, 2009)
Aim: To evaluate the effect of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazole (7-Nl) on hippocampal cell loss induced by zinc hemisulfate salt (ZnSO4-7H2O) treatment. Materials and Methods: Rats were ...
Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity
(Pergamon-Elsevier Science Ltd, 2008)
Iron is a commonly used metal to induce neuronal hyperactivity and oxidative stress. Iron levels rise in the brain in some neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. A body of evidence indicates ...
Nitric oxide synthesis inhibition attenuates iron-induced neurotoxicity: A stereological study
(Elsevier Science Bv, 2008)
Iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders. Therefore, iron is commonly used as a metal to induce neuronal hyperactivity and ...
Neuroprotection by 7-nitroindazole against iron-induced hippocampal neurotoxicity
(Springer/Plenum Publishers, 2007)
(1) Iron plays an important role in maintaining normal brain function. In some neurodegenerative disorders including Parkinson's and Alzheimer's disease, iron levels rise in the brain. It is known that higher iron levels ...