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A concise review of optical, physical and isotropic fractionator techniques in neuroscience studies, including recent developments 

Deniz, Omur Gulsum; Altun, Gamze; Kaplan, Arife Ahsen; Yurt, Kiymet Kubra; von Bartheld, Christopher S.; Kaplan, Süleyman (Elsevier Science Bv, 2018)
Stereology is a collection of methods which makes it possible to produce interpretations about actual three-dimensional features of objects based on data obtained from their two-dimensional sections or images. Quantitative ...

A stereological study of MRI and the Cavalieri principle combined for diagnosis and monitoring of brain tumor volume 

Sonmez, Osman Fikret; Odaci, Ersan; Bas, Orhan; Colakoglu, Serdar; Sahin, Bunyamin; Bilgiç, Sait; Kaplan, Süleyman (Elsevier Sci Ltd, 2010)
In this study, we aimed to describe the application of the Cavalieri principle for the assessment of tumor volume using MRI without an over-projection/estimation effect. For this purpose, the volume of a patient's brain ...

A brief update on physical and optical disector applications and sectioning-staining methods in neuroscience 

Yurt, Kiymet Kubra; Kivrak, Elfide Gizem; Altun, Gamze; Mohamed, Hamza; Ali, Fathelrahman; Gasmalla, Hosam Eldeen; Kaplan, Süleyman (Elsevier Science Bv, 2018)
A quantitative description of a three-dimensional (3D) object based on two-dimensional images can be made using stereological methods These methods involve unbiased approaches and provide reliable results with quantitative ...

The protective effect of curcumin on the diabetic rat kidney: A stereological, electron microscopic and immunohistochemical study 

Ulubay, Mahmut; Alkan, Isinsu; Yurt, Kiymet Kubra; Kaplan, Süleyman (Elsevier Gmbh, 2020)
The prevalence of diabetes in the world is increasing rapidly. Kidney diseases are among the most common medical disorders. The aim of this study was to investigate the effect of curcumin on the diabetic kidney. Thirty-five ...

Possible promoting effects of melatonin, leptin and alcar on regeneration of the sciatic nerve 

Onger, Mehmet Emin; Kaplan, Süleyman; Deniz, Omur Gulsum; Altun, Gamze; Altunkaynak, Berrin Zuhal; Balci, Kemal; Geuna, Stefano (Elsevier, 2017)
Peripheral nerve injury is a widespread and disabling condition that can impair the individual's daily life. Studies involving medications that may positively affect peripheral nerve regeneration are rare. The aim of this ...

The neuroprotective effect of melatonin on the hippocampus exposed to diclofenac sodium during the prenatal period 

Yurt, Kiymet Kubra; Kaplan, Süleyman; Kivrak, Elfide Gizem (Elsevier, 2018)
Melatonin (Mel) has strong antioxidant properties since it is a direct scavenger of oxygen-based free radicals and related species. The main aim of this study is to show whether the effects of Mel can prevent the potential ...

Effects of spermine and the passive avoidance learning (PAL) following cerebral ischemia in chicks: Association with neuroprotection of pyramidal cells 

Kaplan, Süleyman; Onger, M. Emin; Altunkaynak, B. Zuhal; Elibol, Ebru; Deniz, Omur G.; Karayigit, M. Onder; Ragbetli, Murat Cetin (Elsevier Science Bv, 2018)
The aim of this study is to investigate the effects of spermine and the passive avoidance learning on hippocampus following transient cerebral ischemia in the chicks. The study is composed of the pure control (CG), sham ...

Different methods for evaluating the effects of microwave radiation exposure on the nervous system 

Altunkaynak, Berrin Zuhal; Altun, Gamze; Yahyazadeh, Ahmed; Kaplan, Arife Ahsen; Deniz, Omur Gulsum; Turkmen, Aysin Pinar; Kaplan, Süleyman (Elsevier, 2016)
Microwave radiation (MWR) leads to hazardous effects on he central nervous system (CNS) for both human and animals. The widespread use of mobile phones has increased the risks of health problems in the CNS caused by ...

Prenatal exposure to diclofenac sodium changes the morphology of the male rat cervical spinal cord: A stereological and histopathological study 

Ozyurt, Birsen; Kesici, Hakan; Alici, S. Kubra; Yilmaz, Saadet; Odaci, Ersan; Aslan, Huseyin; Kaplan, Süleyman (Pergamon-Elsevier Science Ltd, 2011)
Diclofenac sodium is one of the most commonly used non-steroidal anti-inflammatory drugs. It may cause alteration in the nervous system during neuronal development. However, there is no investigation concerning its role ...

Nitric oxide synthase inhibitors protect cerebellar Purkinje cells from zinc-induced cell loss in adult rat 

Gokce, Mehmet Fatih; Kaplan, Süleyman; Turkkani, Ayten; Kozan, Ramazan; Ayyildiz, Mustafa; Emirzeoglu, Mehmet; Marangoz, Cafer (Elsevier Science Bv, 2011)
Zinc is an important trace element in biological systems; however, excessive extracellular zinc could lead to neuronal cell death following ischemia, seizures, and brain trauma. In this study, we investigated whether the ...
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