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Effects of melatonin on diclofenac sodium treated rat kidney: a stereological and histopathological study 

Khoshvakhti, Habib; Yurt, K. Kubra; Altunkaynak, B. Zuhal; Turkmen, Aysin P.; Elibol, Ebru; Aydin, Isinsu; Kaplan, Süleyman (Taylor & Francis Ltd, 2015)
Objective: In this study, we aimed to investigate the effect of diclofenac sodium (DS) and melatonin (MEL) on kidney of the prenatally administered rats. Materials and methods: Pregnant rats were divided into the control, ...

Periaqueductal Grey Stimulation Induced Panic-Like Behaviour Is Accompanied by Deactivation of the Deep Cerebellar Nuclei 

Moers-Hornikx, Veronique M. P.; Vles, Johan S. H.; Lim, Lee Wei; Ayyildiz, Mustafa; Kaplan, Süleyman; Gavilanes, Antonio W. D.; Temel, Yasin (Springer, 2011)
Until recently, the cerebellum was primarily considered to be a structure involved in motor behaviour. New anatomical and clinical evidence has shown that the cerebellum is also involved in higher cognitive functions and ...

The histopathological and stereological assessment of the effect of topically administered leptin on cerebral vasospasm in an experimental subarachnoid hemorrhage model 

Demirel, Cem; Cokluk, Cengiz; Aksoy, Abdurrahman; Aydin, Kerameddin; Onger, Mehmet Emin; Kuruoglu, Enis; Kaplan, Süleyman (Tubitak Scientific & Technical Research Council Turkey, 2017)
Background/aim: Cerebral vasospasm is a term that refers to prolonged, slowly progressing but reversible pathological narrowing of cerebral arteries occurring several days after subarachnoid hemorrhage (SAH), usually ...

Effects of diclofenac sodium on the hippocampus of rats with acute subdural hematoma: histological, stereological, and molecular approach 

Turkmen, Aysin Pinar; Kaplan, Süleyman; Aksoy, Abdurrahman; Altunkaynak, Berrin Zuhal; Yurt, Kiymet Kubra; Elibol, Ebru; Onger, Mehmet Emin (Termedia Publishing House Ltd, 2016)
This study was aimed at evaluating the potential effects of acute subdural hematoma (ASDH) and diclofenac sodium (DS) therapy following ASDH on the rat hippocampus. Twenty-four male Sprague Dawley rats were used and divided ...

Immediate versus delayed primary nerve repair in the rabbit sciatic nerve 

Piskin, Ahmet; Altunkaynak, Berrin Zuhal; Citlak, Atilla; Sezgin, Hicabi; Yazici, Ozgur; Kaplan, Süleyman (Wolters Kluwer Medknow Publications, 2013)
It is well known that peripheral nerve injury should be treated immediately in the clinic, but in some instances, repair can be delayed. This study investigated the effects of immediate versus delayed (3 days after injury) ...

Effects of thymoquinone on testicular structure and sperm production in male obese rats 

Tufek, Nur Hande; Altunkaynak, Muhammad Eyup; Altunkaynak, Berrin Zuhal; Kaplan, Süleyman (Taylor & Francis Inc, 2015)
Thymoquinone (TQ) is a phytochemical compound found in the plant Nigella sativa. It has antioxidant and anti-cancer effects. This study investigated the effects of TQ on obesity and testicular structure of high-fat-diet ...

Prenatal exposure of diclofenac sodium affects morphology but not axon number of the median nerve of rats 

Ayranci, Ebru; Altunkaynak, Berrin Zuhal; Aktas, Abit; Ragbetli, Murat C.; Kaplan, Süleyman (Termedia Publishing House Ltd, 2013)
The present study examined the effect of DS exposure on median nerve development in rats during prenatal life. Pregnant female rats were divided into three groups: a control group, a saline group and a DS group. Offspring ...

A Study on the Toxic Effect of Different Doses of Diclofenac Sodium on the Development of the Kidney in the Postnatal Period 

Mustafa, Hesham N.; Alkan, Isinsu; Dentz, Omur Gulsum; Altunkaynak, Berrin Zuhal; Annac, Ebru; Kaplan, Süleyman (Soc Chilena Anatomia, 2019)
The toxic effects of different doses of diclofenac sodium (DS) on the kidney on the postnatal period (0-7 days) by morphometrical and immunohistochemical methods were investigated. For this purpose, 15 female adult wistar ...

The effects of different doses of diclofenac sodium on newborn rat hippocampus exposed during the third trimester 

Elibol, Ebru; Kaplan, Süleyman; Altun, Gamze; Aksoy, Abdurrahman; Altunkaynak, Berrin Zuhal (Scientific Technical Research Council Turkey-Tubitak, 2020)
The main aim of the present study was to examine the neurotoxic effects of prenatal exposure to varying doses of diclofenac sodium (DS) on the rat hippocampus. Twenty-eight Wistar albino adult female rats weighing 280-300 ...

A concise review of optical, physical and isotropic fractionator techniques in neuroscience studies, including recent developments 

Deniz, Omur Gulsum; Altun, Gamze; Kaplan, Arife Ahsen; Yurt, Kiymet Kubra; von Bartheld, Christopher S.; Kaplan, Süleyman (Elsevier Science Bv, 2018)
Stereology is a collection of methods which makes it possible to produce interpretations about actual three-dimensional features of objects based on data obtained from their two-dimensional sections or images. Quantitative ...
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