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Acute and long-term genotoxicity of deltamethrin to insulin-like growth factors and growth hormone in rainbow trout

Aksakal, Ercument; Ceyhun, Saltuk Bugrahan; Erdogan, Orhan; Ekinci, Deniz (Elsevier Science Inc, 2010)

We report here the acute and long-term influences of deltamethrin on the expression of IGF-I, IGF-II and GH-I in rainbow trout muscles. We treated rainbow trouts with different concentrations of deltamethrin (0.25 mu g/L, ...

IGF and GH mRNA levels are suppressed upon exposure to micromolar concentrations of cobalt and zinc in rainbow trout white muscle

Ekinci, Deniz; Ceyhun, Saltuk Bugrahan; Aksakal, Ercument; Erdogan, Orhan (Elsevier Science Inc, 2011)

The objective of this study was to assess the effects of cobalt and zinc exposure of rainbow trout (Oncorhynchus mykiss) on insulin like growth factors (IGF) and growth hormone (GH). Mature rainbow trouts were exposed to ...

Purification and characterization of carbonic anhydrase from the teleost fish Dicentrarchus labrax (European seabass) liver and toxicological effects of metals on enzyme activity

Ceyhun, Saltuk Bugrahan; Senturk, Murat; Yerlikaya, Emrah; Erdogan, Orhan; Kufrevioglu, Omer Irfan; Ekinci, Deniz (Elsevier, 2011)

Carbonic anhydrase (EC 4.2.1.1; CA) was purified and characterized from the liver of the teleost fish Dicentrarchus labrax (European seabass) for the first time. The purification procedure consisted of a single step affinity ...

Deltamethrin attenuates antioxidant defense system and induces the expression of heat shock protein 70 in rainbow trout

Ceyhun, Saltuk Bugrahan; Senturk, Murat; Ekinci, Deniz; Erdogan, Orhan; Ciltas, Abdulkadir; Kocaman, Esat Mahmut (Elsevier Science Inc, 2010)

The current research aims to determine alterations in gene expression and enzymatic activity of fish antioxidant metabolism in response to pesticide administration. To this end, three different deltamethrin concentrations ...

Influence of Cobalt and Zinc Exposure on mRNA Expression Profiles of Metallothionein and Cytocrome P450 in Rainbow Trout

Ceyhun, Saltuk Bugrahan; Aksakal, Ercument; Ekinci, Deniz; Erdogan, Orhan; Beydemir, Sukru (Humana Press Inc, 2011)

The present research aims to evaluate the effects of cobalt and zinc exposure of rainbow trout (Oncorhynchus mykiss) on metallothioneins and cytocrome P450. Mature rainbow trouts were exposed to 10 mg/L CoCl2.6H(2)O and 1 ...

Increasing stocking density causes inhibition of metabolic-antioxidant enzymes and elevates mRNA levels of heat shock protein 70 in rainbow trout

Aksakal, Ercument; Ekinci, Deniz; Erdogan, Orhan; Beydemir, Sukru; Alim, Zuhal; Ceyhun, Saltuk Bugrahan (Elsevier, 2011)

The objective of this study was to determine the effects of stocking density on the activity of glucose 6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD) and glutathione reductase (GR) enzymes in ...

Impact of deltamethrin exposure on mRNA expression levels of metallothionein A, B and cytochrome P450 1A in rainbow trout muscles

Erdogan, Orhan; Ceyhun, Saltuk Bugrahan; Ekinci, Deniz; Aksakal, Ercument (Elsevier Science Bv, 2011)

Metallothioneins (MT) are widely utilized to identify specific responses to heavy metal pollution. In addition, there is evidence demonstrating that in vertebrates MT synthesis is stimulated by different endogenous and ...