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Toplam kayıt 4, listelenen: 1-4
Inhibition of neuronal nitric oxide synthase prevents iron-induced cerebellar Purkinje cell loss in the rat
(Nencki Inst Experimental Biology, 2008)
Iron plays an important role in maintaining normal. brain function. However, in many neurodegenerative diseases abnormal iron accumulation in specific brain regions has been consistently reported. In this study, we ...
Neuroprotective effect of aminoguanidine on iron-induced neurotoxicity
(Pergamon-Elsevier Science Ltd, 2008)
Iron is a commonly used metal to induce neuronal hyperactivity and oxidative stress. Iron levels rise in the brain in some neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. A body of evidence indicates ...
Nitric oxide synthesis inhibition attenuates iron-induced neurotoxicity: A stereological study
(Elsevier Science Bv, 2008)
Iron overload and enhanced hydroxyl radical formation have been implicated as the causative factors of some neurodegenerative disorders. Therefore, iron is commonly used as a metal to induce neuronal hyperactivity and ...
Role of nitric oxide synthesis inhibitors in iron-induced nigral neurotoxicity: A mechanistic exploration
(Taylor & Francis Ltd, 2008)
In the central nervous system, nitric oxide (NO) has been suggested to be a cell-to-cell signaling molecule that regulates guanylyl cyclase, aconitase, and iron regulatory protein. NO is also one of the substances that is ...