Browsing by Author "Ramli, Youssef"

Now showing items 1-3 of 3

Crystal structure and Hirshfeld surface analysis of 3-(4-methoxyphenyl)-1-methyl-4-phenyl-1H-pyrazolo[3,4-d]pyrimidine

El Hafi, Mohamed; Kansiz, Sevgi; Lahmidi, Sanae; Boulhaoua, Mohammed; Ramli, Youssef; Dege, Necmi; Mague, Joel T. (Int Union Crystallography, 2019)

In the title molecule, C19H16N4O, the planar pyrazolopyrimidine moiety is inclined to the attached phenyl rings by 35.42 (4) and 54.51 (6)degrees. In the crystal, adjacent molecules are linked into chains parallel to [110] ...
Synthesis of a novel phenytoin derivative: Crystal structure, Hirshfeld surface analysis and DFT calculations

Guerrab, Walid; Lgaz, Hassane; Kansiz, Sevgi; Mague, Joel T.; Dege, Necmi; Ansar, M.; Ramli, Youssef (Elsevier, 2020)

Hydantoin compounds are important heterocyclic scaffolds and a class of well-known bioactive molecules with a broad spectrum of pharmacological properties. Consequently, considerable efforts have been devoted to the design ...
Synthesis, structural and molecular characterization of 2,2-diphenyl-2H,3H,5H,6H,7H-imidazo[2,1-b][1,3]thiazin-3-one

Guerrab, Walid; Chung, Ill-Min; Kansiz, Sevgi; Mague, Joel T.; Dege, Necmi; Taoufik, Jamal; Ramli, Youssef (Elsevier, 2019)

The thiohydantoin scaffold is of substantial importance and it is commonly used in drug discovery. Herein, a novel thiohydantoin-based compound, namely 2,2-diphenyl-2H,3H,5H,6H, 7H-imidazo[2,1-b] [1,3]thiazin-3-one (PIT) ...