Browsing by Author "Korkmaz, Neslihan"
Now showing items 1-3 of 3
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A highly novel dinickel complex: A hydrogen-bonded anti-skew carboxylate bridge and a 2D supramolecular structure
Korkmaz, Neslihan; Gokce, Aytac Gurhan; Astley, Stephen T.; Aygun, Muhittin; Astley, Demet; Büyükgüngör, Orhan (Elsevier Science Bv, 2009)Reaction of the tridentate Schiff base ligands obtained from 2,4-dihydroxybenzaldehyde and either L-iso-leucine or L-tert-leucine with Ni(NO3)(2) in methanol/water solution in the presence of base afforded dinickel complexes. ... -
Kinetic and docking studies of cytosolic/tumor-associated carbonic anhydrase isozymes I, II and IX with some hydroxylic compounds
Durdagi, Serdar; Korkmaz, Neslihan; Isik, Semra; Vullo, Daniela; Astley, Demet; Ekinci, Deniz; Supuran, Claudiu T. (Taylor & Francis Ltd, 2016)A series of hydroxylic compounds (1-10, NK-154 and NK-168) have been assayed for the inhibition of three physiologically relevant carbonic anhydrase isozymes, the cytosolic isozymes I, II and tumor-associated isozyme IX. ... -
Synthesis and biological activity of novel thiourea derivatives as carbonic anhydrase inhibitors
Korkmaz, Neslihan; Obaidi, Oday A.; Senturk, Murat; Astley, Demet; Ekinci, Deniz; Supuran, Claudiu T. (Taylor & Francis Ltd, 2015)A new series of chiral thiourea derivatives (5a-5c) and thiourea containing benzimidazole moieties (9b-9e) were synthesized from different amino acids (L-valine, L-isoleucine, L-methionine, L-phenylalanine, and D-phenylglycine). ...