Browsing by Author "Bagci, Hasan"
Now showing items 1-20 of 24
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Analysis of vitamin D receptor gene polymorphisms in patients with chronic periodontitis
Gunes, Sezgin; Sumer, A. Pinar; Keles, Gonca Cayir; Kara, Nurten; Koprulu, Hulya; Bagci, Hasan; Bek, Yuksel (Medknow Publications & Media Pvt Ltd, 2008)Background & objectives: Genetic polymorphisms in the vitamin D receptor (VDR) gene are related to bone mineral density, bone turnover, and diseases with bone loss. Alveolar bone loss is a key feature in periodontitis. The ... -
Association between Sport Performance and Alpha-Actinin-3 Gene R577X Polymorphism
Yamak, Bade; Yuce, Melek; Bagci, Hasan; Imamoglu, Osman (Kamla-Raj Enterprises, 2015)Physical performance has been associated with many gene variants including the alpha-actinin-3 gene (ACTN3) R577X polymorphism. The purpose of the present study is to investigate whether there is an association between ... -
Association of eNOS gene polymorphism (Glu298Asp) with psoriasis
Senturk, Nilgun; Kara, Nurten; Aydin, Fatma; Gunes, Sezgin; Yuksel, Esra Pancar; Bagci, Hasan; Turanli, Ahmet Yasar (Elsevier Ireland Ltd, 2006)… -
Association of interleukin-10 gene polymorphisms with severe generalized chronic periodontitis
Sumer, A. Pinar; Kara, Nurten; Keles, Gonca Cayir; Gunes, Sezgin; Koprulu, Hulya; Bagci, Hasan (Wiley, 2007)Background: Interleukin-10 (IL-10), an anti-inflammatory cytokine, plays a role in periodontal disease by inhibiting synthesis of proinflammatory cytokines and stimulating protective antibody production. Genetic polymorphisms ... -
Association of matrix metalloproteinase-9 promoter gene polymorphism with chronic periodontitis
Keles, Gonca Cayir; Gunes, Sezgin; Sumer, A. Pinar; Sumer, Mahmut; Kara, Nurten; Bagci, Hasan; Koprulu, Hulya (Wiley, 2006)Background: Matrix metalloproteinases (MMPs) are related to tissue destruction and remodeling events in periodontal diseases. A single nucleotide polymorphism in the promoter region of human MMP-9 gene is associated with ... -
Association of serotonin 2A receptor and lack of association of CYP1A2 gene polymorphism with tardive dyskinesia in a Turkish population
Boke, Omer; Gunes, Sezgin; Kara, Nurten; Aker, Servet; Sahin, Ahmet Rifat; Basar, Yildiz; Bagci, Hasan (Mary Ann Liebert, Inc, 2007)The aim of this study was to investigate the possible association of serotonin 2A receptor gene (HTR2A) - 1438 G/A polymorphism and CYP1A2 gene 163C/ A polymorphism with tardive dyskinesia (TD) in a Turkish population. A ... -
Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population
Kara, Nurten; Keles, Gonca Cayir; Sumer, Pinar; Gunes, Sezgin Ozgur; Bagci, Hasan; Koprulu, Hulya; Bek, Yuksel (Taylor & Francis Ltd, 2007)Objectives. The etiology of periodontitis is related to the interaction between micro-organisms and host responses. Host modifving factors, such as genetic predisposition, may increase the severity of periodontitis. Recent ... -
Association of transforming growth factor beta 1 gene polymorphism with rheumatoid arthritis in a Turkish population
Alayli, Gamze; Kara, Nurten; Tander, Berna; Canturk, Ferhan; Gunes, Sezgin; Bagci, Hasan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)Objective: Cytokine genes play important role, in the pathogenesis of rheumatoid arthritis (RA). In RA, the plasma and synovial fluid levels of transforming growth factor beta 1 (TGF beta 1) have been shown to be raised. ... -
Clinical significance of MEFV mutations in ankylosing spondylitis
Durmus, Dilek; Alayli, Gamze; Cengiz, Kivanc; Yigit, Serbulent; Canturk, Ferhan; Bagci, Hasan (Elsevier France-Editions Scientifiques Medicales Elsevier, 2009)Objective: The aim of the present study was to investigate the prevalence of MEFV gene mutations in patients with ankylosing spondylitis (AS) and to assess the clinical significance of the MEFV gene mutations in AS. Methods: ... -
Diffuse Multicystic encephalomalacia in a preterm baby due to homozygous methylenetetrahydrofolate reductase 677 C -> T mutation
Aygun, Canan; Tanyeri, Bilge; Ceyhan, Meltem; Bagci, Hasan; Kucukoduk, Sukru (Sage Publications Inc, 2008)Methylenetetrahydrofolate reductase catalyzes the formation of 5-methyltetrahydrofolate from 5,10-methylentetrahydrofolate and produces folate for the methylation of homocysteine to methionine. Due to insufficient conversion ... -
ErbB receptor tyrosine kinase family expression levels in urothelial bladder carcinoma
Gunes, Sezgin; Sullu, Yurdanur; Yegin, Zeynep; Buyukalpelli, Recep; Tomak, Leman; Bagci, Hasan (Elsevier Gmbh, 2013)ErbB receptor tyrosine kinases family plays an important role in cell cycle regulation. Overexpression of ErbB receptors has been described in several solid tumors. The aim of this study was to investigate the levels of ... -
Evaluation of pathergy test positivity in familial Mediterranean fever patients and comparison of clinical manifestations of FMF with Behcet's disease
Aydin, Fatma; Akpolat, Tekin; Senturk, Nilgun; Bagci, Hasan; Turanli, Ahmet Yasar (Springer London Ltd, 2009)Familial Mediterranean fever (FMF) shares a number of features with Beh double dagger et's disease (BD), such as their common ethnic origin, etiopathogenetic mechanisms, symptoms, and treatment. Pathergy reaction is accepted ... -
The frequency of CCR5delta32 polymorphism in the central Black Sea coastal region in a healthy population
Guenes, Sezgin Oezguer; Kara, Nurten; Bagci, Hasan (Tubitak Scientific & Technical Research Council Turkey, 2007)Aim: Delta32 polymorphism in the chemokine receptor 5 (CCR5) gene affects human immune deficiency virus type 1 (HIV-1) entry, transmission, and outcome. The aim of this study was to determine the allelic frequencies of ... -
Interaction Between Periodontal Disease and Systemic Secondary Amyloidosis: From Inflammation to Amyloidosis
Cengiz, Murat Inanc; Yayla, Nazir; Cengiz, Kuddusi; Bagci, Hasan; Taskin, Emre (Amer Acad Periodontology, 2011)Background: It has become increasingly clear in recent years that periodontal disease can cause a dramatic increase in the levels of markers of systemic inflammation, and that periodontal treatment can result in reduction ... -
Is there any relationship between human foamy virus infections and familial Mediterranean fever?
Yuce, Melek; Bagci, Hasan; Cengiz, Kuddusi (Wolters Kluwer Medknow Publications, 2018)Background: Familial Mediterranean fever (FMF) is generally defined as an autosomal recessive disease, characterized by the automatic activation of the innate immune system in the absence of a detectable pathogenic stimulant. ... -
Lack of Association Between Interleukin 6 Gene Promoter Polymorphisms and Aneurysmal Subarachnoid Hemorrhage in Turkish Population
Bayri, Yasar; Taskin, Emre; Ulus, Aykan; Bayrakli, Fatih; Altun, Adnan; Bagci, Hasan (Journal Neurological Sciences, 2015)Background: The IL6 gene is related to several disease states. Its relation to aneurysm formation and aneurysmal SAH has been studied in the literature, but the reported results have not resulted in definite positive or ... -
Lack of association between the G-2548A polymorphism of the leptin gene and psoriasis in a Turkish population
Kara, Nurten; Aydin, Fatma; Senturk, Nilgun; Gunes, Sezgin; Canturk, M. Tayyar; Bagci, Hasan; Turanli, Ahmet Yasar (Blackwell Publishing, 2007)Background Psoriasis is a multifactorial disease in which genetic and inflammatory factors play important roles. Leptin is classified as a cytokine and plays an important role in the regulation of the T-helper response. A ... -
MEFV mutations in patients with familial Mediterranean fever in the Black Sea region of Turkey
Yigit, Serbulent; Bagci, Hasan; Ozkaya, Ozan; Ozdamar, Kazim; Cengiz, Kuddusi; Akpolat, Tekin (J Rheumatol Publ Co, 2008)Objective. To investigate MEFV mutations among patients with familial Mediterranean fever (IMF), their relatives, and healthy controls in the Black Sea region of Turkey; to compare 3 different MEFV mutation analysis methods; ... -
P53 Codon 72 and HER2 Codon 655 Polymorphisms in Turkish Breast Cancer Patients
Kara, Nurten; Karakus, Nevin; Ulusoy, Ali Naki; Ozaslan, Cihangir; Gungor, Bulent; Bagci, Hasan (Mary Ann Liebert Inc, 2010)The polymorphisms in codon 72 of the tumor suppressor protein p53 (P53) gene and codon 655 of the human epidermal growth factor receptor 2 (HER2) gene have been suggested to play roles in most cancers. The purpose of this ... -
Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility
Tander, Berna; Gunes, Sezgin; Boke, Omer; Alayli, Gamze; Kara, Nurten; Bagci, Hasan; Canturk, Ferhan (Springer Heidelberg, 2008)Genetic and environmental factors are thought to play roles in the etiopathology of fibromyalgia syndrome (FMS). The objective of this study was to determine the potential effects of single nucleotide polymorphisms (SNPs) ...
